Senorx, Inc.

Other

Stephen A De Santis

Paul Lubock

Richard L Quick

Michael L Jones

Fred H Burbank

Frank R Louw

The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

Tissue site markers for in vivo imaging

Tissue site markers for in VIVO imaging

A needle core biopsy instrument/extractor for extracting a tissue sample via needle aspiration is disclosed. The extractor comprises a first cannula having a sharpened, beveled cutting tip and biopsy reservoir formed on it distal end. The proximal end of the first cannula is in fluid communication with a conventional syringe such that when the plunger of the syringe is retracted via manipulation o the extractor, a vacuum is created within the biopsy reservoir of the first cannula Axially mounted about the first cannula is a second cutting cannula which is designed and configured to selectively cover and uncover the distal end of the first cannula. A biasing member, preferably a spring, is provided to urge the second cannula forward about the distal end of the first cannula. The syringe, coaxially positioned first and second cannulas, and biasing member are contained within an introducer which is preferably designed and configured to be manipulated by one hand. The handle slide and lever of the device are oriented in such a way as to allow the retention of tissue via vacuum and the severing of the specimen by the second cannula to be exactly timed by cam operation.

Needle core biopsy instrument with durable or disposable cannula assembly

A fine needle aspiration cytology device for extracting tissue samples for cytologic evaluation is disclosed. The device comprises a handle and generally U-shaped slide member with trigger attachable thereto. The handle is designed and configured to releasably engage a conventional syringe. The slide is designed to slidably engage with the handle and is provided with a slot at the base thereof for retaining the plunger of the When interconnected, the slide may move in forward or rearward positions relative the handle and further, when interconnected with a syringe, may selectively control the axial position of the plunger relative the syringe. In a preferred embodiment, the device is further provided with a manually adjustable locking detent mechanism that may releasably maintain the handle and slide in rigid connection.

Fine needle aspiration cytology device syringe holder

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Laguna Niguel, CA, United States of America

Stephen A De Santis