Starpharma Pty Limited

Stephanie Ruth Edmondson

Brian Devlin Kelly

David James Owen

Jacinth Kincaid Fairley

Jeremy Robert Arthur Paull

Nicola Jane Main

Provided herein are dendrimers comprising: a core unit, five generations of building units which are lysine residues or analogues thereof, first terminal groups comprising a cabazitazel residue covalently attached to a diglycolyl linker group, and second terminal groups comprising a PEG group. Also provided herein are pharmaceutical compositions comprising the dendrimers, and methods and uses of the dendrimers in therapy of disorders such as cancers. Processes for making the dendrimers and intermediates are also provided.

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Preston, Australia

Stephanie Ruth Edmondson