St. Jude Medical, Cardiology Division, Inc.

Hydrogenics Corporation

University Health Network

Stéphane Massé

D Curtis Deno

Don Curtis Deno

Dennis J Morgan

Ram Kumar Balachandran

Kumaraswamy Nanthakumar

Joshua C Bush

Karl Magtibay

Ravi B Gopal

Norman A Freeman

Pierre Rivard

Stephen Burany

Eugene Downar

Donald C Deno

The disclosure relates generally to applications of Orientation Independent Sensing (OIS) and Omnipolar mapping Technology (OT) to various system, device and method embodiments as recited herein. Similarly, systems and methods suitable for supporting OIS and OT systems and methods are disclosed. Further, OIS and OT implementations that provide end user interfaces, diagnostic indicia and visual displays generated, in part, based on measured data or derived from measured data are also disclosed. Embodiments also describe applying optimization techniques to determine the greatest voltage difference of a local electric field associated with an electrode-based diagnostic procedure and a vector representation thereof. Various graphic user interface related features are also described to facilitate orientation and electrode clique signal display.

Orientation independent sensing, mapping, interface and analysis systems and methods

A system and method for obtaining an OIS coordinate frame comprising an electronic control unit configured to determine a local 3D electric field loop, create a zero mean version of E(t) over a depolarization interval, compute an &#x116; value at each of a plurality of time intervals, compute an initial estimate of &#x175; from a cross product of E and the &#x116; value for each of the plurality of time intervals, average the initial estimate of &#x175; from each of the plurality of time for a best estimate of &#x175;, determine a plurality of &#xe2;(&#x3b8;) values and using the corresponding {circumflex over (n)}(&#x3b8;) values, compute a composite match score, and choose at least one best value for &#xe2; and a best value for {circumflex over (n)}.

Systems and methods for orientation independent sensing

Various embodiments are described herein for a system and a method for identifying the arrhythmogenic circuit of a patient or subject. In one embodiment, the method comprises obtaining data for electrograms recorded at various locations of the heart while programmed ventricular pacing with extra stimuli was performed, obtaining decrement values for at least two different locations of the heart using the recorded electrograms, generating at least a portion of a decrement map using the decrement values, and identifying the arrhythmogenic circuit based on electrograms having significant decremental properties.

System and method for Decrement EvokEd Potential (DEEP) mapping to identify components of the arrythmogenic circuit in cardiac arrhythmias

A system and method for monitoring cell voltages for a plurality of electrochemical cells connected in series forming a cell stack. The method includes dividing the cells into at least two cell groups, measuring the voltage across each cell group and estimating the minimum cell voltage for each group based on the average cell stack voltage and an estimated number of deficient cells in each group. The lowest minimum cell voltage for the entire cell stack is then determined.

Method and apparatus for monitoring fuel cell voltages

This invention discloses a self-contained, portable, cost-effective apparatus for measuring the real and imaginary components of a fuel cell's complex impedance at discrete frequencies. The apparatus comprises a CPU, a signal generation device, a fuel cell, a load bank, current and voltage sensing circuitry and a waveform acquisition device. The measurements can be done in real time and automated. The fuel cell's internal resistance can be calculated thereby providing an indication of the electrical efficiency of the fuel cell.

Measurement of fuel cell impedance

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Toronto, Canada

Stéphane Massé