Societe Des Produits Nestle S.a.

Nestec S.a.

Soceite Des Produits Nestle S.a.

Stephane Duboux

Serge Andre Dominique Rezzi

Philippe Alexandre Guy

Bertrand Bourqui

Nicolas Page

Christina Vafeiadi

Francia Jacqueline Arce Vera

Francis Foata

Timo Buetler

Laure Poquet

Christof Gysler

Marie Noelle Horcajada

Yvette Fleury Rey

Carl Erik Hansen

Catherine Ngom-Bru

Sander Sebastiaan Van Leeuwen

Lubbert Dijkhuizen

Joana Gangoiti Munecas

Cassandra Mokdad

Clementine Tastet

Florence Rochat

Annick Mercenier

Rachid Bel-Rhlid

Marjorie Guitard

Gabriela Bergonzelli Degonda

Sylvain Lengacher

Pierre Julius Magistretti

Jane Durga

Lisa Marcela Lamothe

Rosa ARAGÃO BÖRNER

Tjaard Pijning

Evelyne Ruchti

Igor Allaman

Kaori Minehira Castelli

Muzi Tangyu

The present invention relates to aprobiotic for use to improve fermentability of a plant fibre during gastro-intestinal tract passage in a subject, wherein said plant fibre has an insoluble fraction of between 40 to 80% (w/w).

Insoluble fibre fermentability and short chain fatty acid production by

The present invention relates to flavour generation. In particular the invention relates to a method for flavour generation in a heat-treated food product using a prolidase enzyme. The invention also relates to a heat-treated food product prepared according to the method of the invention.

Flavour generation in food

Use of a sugar selected from lactose, fructose and raffinose, for increasing serpin expression instrain CNCM I-2618.

Serpin production

A composition contains at least one probiotic or enzyme selected from the group consisting of (i) a probiotic having &#x3b2;-glycosidase activity or a &#x3b2;-glycosidase, (ii) a probiotic having esterase activity or an esterase, (iii) a probiotic having both &#x3b2;-glycosidase activity and esterase activity or an enzyme having both &#x3b2;-glycosidase activity and esterase activity, (iv) a first probiotic having &#x3b2;-glycosidase activity and a second probiotic having esterase activity, (v) a probiotic having &#x3b2;-glycosidase activity and an esterase, (vi) a &#x3b2;-glycosidase and a probiotic having esterase activity and (vii) a &#x3b2;-glycosidase and an esterase. The at least one probiotic can form one or more of oleuropein aglycone, elenolic acid, hydroxytyrosol acetate or hydroxytyrosol from oleuropein. The composition can comprise oleuropein. The composition can be for treating or preventing impaired mobility in an older adult; stimulating bone formation and/or inhibiting bone resorption; treating or preventing synovitis in an individual in need or at risk thereof or treating or preventing articular cartilage degradation subsequent to synovitis in an individual having or recovering from synovitis; or preventing or treating cartilage breakdown.

Bioconversion of oleuropein

The present invention relates generally to probiotics, in particular probiotics capable of bio-converting olive polyphenols. The invention relates to a method of selecting a probiotic strain or probiotic strain mixture. Further aspects of the invention include the use of a probiotic strain to increase the bio-efficacy of olive polyphenols and a composition comprising a probiotic strain for use in the potentiation of a therapeutic effect and/or a prophylactic effect of oleuropein.

Method of selecting a probiotic

The present invention relates to the field of poly- and oligosaccharides and their dietary effects. In particular it relates to a method of producing a branched &#x3b1;-glucan. Further aspects of the invention are a branched &#x3b1;-glucan comprising linear segments of (&#x3b1;1&#x2192;4) linked D-glucose units interspersed with (&#x3b1;1&#x2192;6) glucosidic linkages and having (&#x3b1;1&#x2234;4,6) branching points; a food composition; and the use of an &#x3b1;-glucanotransferase enzyme for reducing the digestible carbohydrates of a starch containing food material.

Branched alpha glucans

The present invention relates to the field of poly- and oligosaccharides and their dietary effects. In particular it relates to a method of producing an &#x3b1;-glucan containing (&#x3b1;1&#x2192;3) linked D-glucose units. The invention also provides a branched &#x3b1;-glucan comprising alternating (&#x3b1;1&#x2192;4) and (&#x3b1;1&#x2192;3) glucosidic linkages and having (&#x3b1;1&#x2192;3,4) branching points, a food composition, and the use of an &#x3b1;-glucanotransferase enzyme for reducing the digestible carbohydrates of a starch containing food material. Further aspects of the invention are a bacteria, an enzyme and an expression vector.

Alpha glucans

The present invention relates to a method of forming dihydroferulic acid comprising providing ferulic acid and incubating the ferulic acid with a bacterial preparation ofCNCM 1-1225 or a bacterial preparation of natural derivatives ofCNCM 1-1225. An aspect of the invention is a composition comprising dihydroferulic acid and a bacterial preparation ofCNCM 1-1225 or its natural derivatives. A further aspect of the invention is a composition comprising ferulic acid and a bacterial preparation ofCNCM 1-1225 or its natural derivatives for use in the treatment or prevention of metabolic disease. Further aspects of the invention are the use of a bacterial preparation ofCNCM 1-1225 or its natural derivatives; and a kit for preparing a food product.

Method of forming dihydroferulic acid

The present invention relates generally to the field of enhancing skin appearance. One aspect of the invention aims to provide a composition comprising 4-oxo-2-pentenoic acid for use in the reduction or prevention of regions of the skin with darker pigmentation. The present invention also relates to cosmetic use of a composition comprising 4-oxo-2-pentenoic acid for the reduction or prevention of regions of the skin with darker pigmentation.

4-oxo-2-pentenoic acid and skin pigmentation

The present invention relates generally to compositions with a health benefit. In particular, the invention relates to treatment or prevention of liver disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders. A further subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders linked to an insufficient activity of phase II enzymes in the liver.

4-oxo-2-pentenoic acid and liver disorders

The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of brain health, for example brain protection, maintenance of cognitive function, prevention of cognitive decline and prevention of cognitive disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cognitive decline.

4-oxo-2-pentenoic acid and brain health

The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of cardiovascular disorders, for example, atherosclerosis, high blood pressure, coronary heart disease, myocardial infarction, angina pectoris, stroke, and heart failure. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cardiovascular disorders.

4-oxo-2-pentenoic acid and cardiovascular health

Growing community of inventors

St-Prex, Switzerland

Stephane Duboux