Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v.

Stephan Quint

Michael Bassler

Michael Baβler

Embodiments relate to a device (), a method and a computer program for providing information on at least one sequence, wherein the at least one sequence describes temporally successive signal states, comprising a device (), a method and a computer program for a cytometer () for providing information on one or several cells in a medium in a channel and comprising a cytometer (). The device () comprises an interface (), which is configured to receive information on a number of the signal states. The device () a computational module () which is configured to generate a plurality of possible sequences based on the information on the number of the signal states. The computational module () is further configured to calculate for at least a subset of the possible sequences correlation functions between a sequence and at least a temporal scaling of the sequence, wherein a correlation function includes a main lobe and one or several side lobes. The computational module () is further configured to determine the at least one sequence based on the correlation functions, wherein the order of the signal states within the at least one sequence is selected such that a side lobe in a correlation function of the sequence comprising the at least one temporal scaling of the sequence is reduced as compared to a side lobe which may maximally be acquired in a correlation function by different arrangements of the signal states in the sequence, and to determine the information on the at least one sequence based on the at least one sequence and provide the same via the interface ().

Devices, cytometers, methods and computer program for providing information on at least one sequence

The present invention concerns a method of detecting particles which move along a trajectory and which produce or at least influence electromagnetic radiation, an electrical field or a magnetic field, wherein the electromagnetic radiation, the electrical field or the magnetic field is detected, in which a structuring device is used, which either ensures that the particles along the trajectory produce or at least influence electromagnetic radiation, an electrical field or a magnetic field substantially only at non-periodic spatial spacings, or ensures that the electromagnetic radiation, the electrical or the magnetic field is detected substantially only at non-periodic spatial spacings along the trajectory. To provide a method of detecting particles which move along a trajectory and which produce or at least influence electromagnetic radiation, an electrical field or a magnetic field, it is proposed according to the invention that the detected signal S is processed by means of a mismatched filter Fand if the signal D(S) filtered in that way fulfils a predefined threshold criterion a particle is detected and if the signal filtered in that way does not fulfill the predefined threshold criterion no particle is detected.

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Dortmund, Germany

Stephan Quint