St Jude Medical, Atrial Fibrillation Division, Inc

St. Jude Medical, Cardiology Division, Inc.

Stephan Paul Miller

Don Curtis Deno

D Curtis Deno

Saurav Paul

Liane R Teplitsky

Glen H Kastner

Haris Sih

Yuriy Malinin

Ryan Albu

Lewis C Hill

Michael S Bowers

Robert D Aiken

Anthony Knutson

Donald Curtis Deno

Ryan M Albu

A system and method for assessing effective delivery of ablation therapy to a tissue in a body is provided. A three-dimensional anatomical map of the tissue is generated and displayed with the map defining a corresponding volume. An index is generated corresponding to a location within the volume with the index indicative of a state of ablation therapy at the location. The index may be derived from one or more factors such as the duration an ablation electrode is present at the location, the amount of energy provided, the degree of electrical coupling between an ablation electrode and the tissue at the location and temperature. A visual characteristic (e.g., color intensity) of a portion of the anatomical map corresponding to the location is then altered responsive to the index.

System and method for assessing effective delivery of ablation therapy

A catheter and patch electrode system is provided for use with an apparatus, such as an ablation generator, having a 4-wire interface for improved impedance measurement. The 4-wire interface includes a pair of source connectors across which an excitation signal is produced and a pair of sense connector wires across which the impedance is measured. The RF ablation generator may also produce an ablation signal across a source wire and an indifferent return patch electrode. The system further includes a cable that connects the generator to a catheter. The catheter includes a shaft having a proximal end and a distal end, with an ablation tip electrode disposed at the distal end. A source lead is electrically coupled to the tip electrode and extends through the shaft to the proximal end where it is terminated. An optional sense lead is also electrically coupled to the tip electrode and extends through the shaft to the proximal end. The system further includes a source return (e.g., skin patch) and a sense return (e.g., skin patch), either or none of which may be combined with the indifferent return, and if used may be placed on opposite sides of the patient for improved performance. The impedance sensor circuit produces an excitation signal across the source connectors, which is then carried to the catheter by the cable, then to the tip electrode, travels through the complex load (tissue volume), and returns to the generator via a patch electrode. The impedance is measured by observing the voltage drop across the sense connectors caused by the excitation signal.

System and method for measurement of an impedance using a catheter such as an ablation catheter

A method and system for assessing lesion formation in tissue is provided. The system includes an electronic control unit (ECU). The ECU is configured to acquire values for first and second components of a complex impedance between the electrode and the tissue, and to calculate an index responsive to the first and second values. The ECU is further configured to process the ECI to assess lesion formation in the tissue.

System and method for assessing lesions in tissue

A method and system for assessing proximity between an electrode and tissue is provided. The system includes an electronic control unit (ECU). The ECU is configured to acquire values for first and second components of a complex impedance between the electrode and the tissue, and to calculate an electrical coupling index (ECI) responsive to the first and second values. The ECU is further configured to process the ECI to determine the proximity of the electrode to the tissue. The ECU may be configured to calculate an electrical coupling index rate (ECIR) based on the calculated ECI and information relating to the change in location of the electrode, and to assess proximity based on the ECIR. Alternatively, the ECU may be configured to assess the proximity using the calculated ECI, as opposed to the ECIR.

System and method for assessing the proximity of an electrode to tissue in a body

A medical device includes an elongate body having a proximal end and a deflectable distal region, a handle coupled to the proximal end, an actuator movable relative to the handle, and a resistance assembly adjacent the actuator. The resistance assembly exerts a force on the actuator that varies according to a direction in which the actuator is moving relative to the handle. For example, the resistance assembly can exert a lower (or zero) force when the actuator is moving relative to the handle in a direction that effects deflection of the distal region of the elongate body from neutral and higher when the actuator is moving relative to the handle in a direction that effects return of the distal region of the elongate body towards neutral. The resistance assembly can also include materials that exhibit anisotropic frictional properties and/or have surface finishes or treatments that yield directionally-dependent frictional forces.

Actuator restraining assembly for medical device

A medical device assembly comprises a medical device comprising a shaft having proximal and distal end portions. The device further comprises a sensor at the distal end portion of the shaft that comprises first and second leads extending therefrom to the proximal end portion of the shaft. The device further comprises an electromechanical connector having a plurality of pins at a first end thereof. First and second of the pins are electrically connected to the first and second sensor leads, respectively, thereby forming a first partial magnetic loop between the first and second pins. The connector further comprises first and second jumpers electrically connecting the first pin and third pins, and second and fourth pins, respectively, thereby forming a second partial magnetic loop. The partial magnetic loops are configured to combine with partial magnetic loops of another connector to form a pair of magnetic noise cancellation loops.

Magnetic field-compatible components of a medical diagnostic and/or therapeutic system

A system and method for assessing a degree of coupling between an electrode and tissue in a body is provided. Values for first and second components of a complex impedance (e.g., resistance and reactance or impedance magnitude and phase angle) between the electrode and the tissue are obtained. These values are used together with a standardization value indicative of a deviation from a reference standard by a parameter associated with at least one of the body, the electrode and another component of the system to calculate a coupling index that is indicative of a degree of coupling between the electrode and the tissue. The coupling index may be displayed to a clinician in a variety of ways to indicate the degree of coupling to the clinician. The system and method find particular application in ablation of tissue by permitting a clinician to create lesions in the tissue more effectively and safely.

System and method for assessing coupling between an electrode and tissue

A system and method for assessing a degree of coupling between an electrode and tissue in a body is provided. Values for first and second components of a complex impedance (e.g., resistance and reactance or impedance magnitude and phase angle) between the electrode and the tissue are obtained. From these values, a coupling index is calculated that is indicative of a degree of coupling between the electrode and the tissue. The coupling index may be displayed to a clinician in a variety of ways to indicate the degree of coupling to the clinician. The system and method find particular application in ablation of tissue by permitting a clinician to create lesions in the tissue more effectively and safely.

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Vadnais Heights, MN, United States of America

Stephan Paul Miller