Basf Aktiengesellschaft

Basf Se Corporation

Stephan Kothrade

Axel Sanner

Gunther Berndl

Helmut Meffert

J&ouml;rg Breitenbach

Volker Schehlmann

Dirk Simon

Peter H&ouml;ssel

Werner Maier

Armin Lange

Rainer Blankenburg

Andreas Kleinke

Joerg Rosenberg

Manfred Niessner

Hans Renz

Claudia Nilz

Thomas Kessler

Stefan Stein

Ulrich Reinhold

Katrin Zeitz

Anton Negele

Reinhold Dieing

Folker Ruchatz

Peter Hössel

Karl Haberle

Andreas Ernst

Harald Krull

Hans-Jürgen Raubenheimer

Brigitta Huckestein

Hans-J&uuml;rgen Raubenheimer

Iris Peters

Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric binder.

Process for producing solid dosage forms

A process for producing solid dosage forms by mixing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives to form a plastic mixture, and shaping, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric binder.

Compositions comprising at least one water-insoluble ingredient and at least one copolymer of

Compositions comprising copolymers of N-vinylcarboxamides and monomers with a hydrophobic radical, and use of these copolymers

High molecular weight mass cationic copolymers

Solid dosage forms are obtained by mixing at least one polymeric binder, at least one active ingredient, and, where appropriate, conventional additives to form a plastic mixture, and shaping, using as polymeric binder a copolymer of an N-vinyllactam and a copolymerizable monomer having a hydrophobic radical. Dosage forms which show slow release of the active ingredient are obtained in a simple and low-cost manner.

Method for producing solid dosing forms

A process for producing solid dosage forms, in which (i) a plastic mixture of at least one pharmacologically acceptable polymeric binder with a K value of more than 75, at least one pharmaceutical active ingredient and, where appropriate, conventional pharmaceutical additives is prepared and (ii) the plastic mixture is shaped to the required dosage form, with step (i) being carried out under conditions of temperature and shear energy input such that the reduction in molecular weight of the polymeric binder, expressed as the difference in the K value, is less than 15 is described.

The invention relates to a process for producing coated solid dosage forms by forming a plastic mixture from at least one thermoplastic physiologically tolerated polymeric binder and at least one active ingredient and extruding the plastic mixture, wherein the extrudate is subsequently treated with at least one liquid or vaporized coating agent, and the coated extrudate is shaped to the required dosage form.

Process for producing coated solid dosage forms

The present invention relates to a solid dosage form comprising at least one polymeric binder and at least one active ingredient and, where appropriate, conventional additives, wherein the polymeric binder consists of copolymerized units a) 15-83% by weight of at least one N-vinyllactam, b) 15-83% by weight of methyl methacrylate, c) 2-70% by weight of at least one other monomer and d) 0-9.9% by weight of at least one &agr;,&bgr;-ethylenically unsaturated acid.

Solid dosage form with polymeric binder

Use of water-soluble copolymers as active ingredients in cosmetics

A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

Process for producing solid dosage forms by extrusion

A process for preparing highly concentrated aqueous solutions of low molecular mass homopolymers of N-vinylpyrrolidone by free-radical solution polymerization in an aqueous medium with H,O,as initiator comprises carrying out the polymerization in the presence of from 0.1 to 30% by weight, based on N-vinylpyrrolidone, of a polymerization regulator which is selected from the group consisting of C,-C,-alkanols, hydroxylamine salts and water-soluble compounds containing sulfur in bonded form.

Preparation of low molecular mass homopolymers of N-vinylpyrrolidone

The present invention relates to a novel process for preparing water-soluble copolymers of at least one water-soluble N-vinyllactam of the formula I ##STR1## where n=1 or 2, and at least one hydrophobic comonomer having a water-solubility of 1 to 85 g/l, by free-radical polymerization in aqueous solution.

Preparation of water-soluble copolymers of at least one water-soluble

Use of copolymers of N-vinylprrolidone in preparations of

Water-emulsifiable polyisocyanates containing

Water-emulsifiable polyisocyanates

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Limburgerhof, Germany

Stephan Kothrade