Roche Diagnostics Operations, Inc.

Roche Diabetes Care, Inc.

Roche Molecular Systems, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Stephan Korner

Emad Sarofim

Carlo S Effenhauser

Irio Giuseppe Calasso

Heinz-Michael Hein

Claudio Cherubini

Patrick Griss

Andreas Drechsler

Rainer Jaeggi

Goran Savatic

Michael Glauser

Edwin Oosterbroek

Reto Abt

Mario Curcio

Rijk Edwin Oosterbroek

Brigitte Niederberger

Irio Guiseppe Calasso

Marko Simic

Marco Simic

Hans-Peter Wahl

Griss Patrick

Oliver Bründler

Désirée Decker

Robert Partel

The present disclosure relates to a method for isolating a biological target material from a liquid sample in a multiwell plate using magnetic particles, wherein high efficiency and low elution volumes are achieved by specific movements of the multiwell plate and a magnetic separation plate in relation to each other. Also disclosed is a pre-analytical system suitable for carrying out the method.

Method for processing a biological sample with magnetic particles

A system for withdrawing blood from a body part that avoids formation of a drop of blood on the skin surface of the body part after blood removal. The system includes a collecting unit to withdraw blood, a lancing member configured for insertion into the body part and having a capillary to collect blood, and a pressure piece configured to apply pressure to the body part and having an actuator operably connected thereto. The pressure piece is movable relative to a support configured to exert pressure on the body part, and the actuator is configured to reduce the compressive force of the pressure piece after removing an amount of blood, whereby forming a drop of blood on the skin surface of the body part can be avoided.

Method and system for withdrawing blood

Centrifugal force based microfluidic systems for the automated analysis of fluids involving the use of magnetically responsive particles and methods thereof are disclosed. A magnet is fixed to a supporting device of the system in correspondence to a retention zone of the system so as to rotate therewith and to generate a magnetic field which magnetically manipulates the magnetically responsive particles contained in a reaction chamber of the system.

Centrifugal force based microfluidic system and method for the automated analysis of samples

A system and method for carrying out the withdrawal of body fluid with as little body fluid as possible visible to the user at the end of the process. The present invention provides a pressure piece for exerting pressure on a body part. The pressure piece is moved relative to a support for the body part, and in the final phase of fluid withdrawal, the compressive or resistive force of the pressure piece on the body part is reduced in order to avoid the escape of body fluid from the puncture site. The support results in a defined positioning of the body part that rests against it for the lancing process, whereas the relative movement of the pressure piece enables an additional increase in pressure and thus an improved collection of fluid.

Method and system for withdrawing body fluid

A device for sampling, transporting and/or disposal of fluid media in the nl and &#x3bc;l-range comprises a substrate with an open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open or closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.

Bent microstructures for sampling, transporting or dispensing a fluid media

The present invention provides a method and a device for piercing a body part and determining whether a sufficient volume of blood has been withdrawn. A lancing element is rapidly inserted into a body part in a forward phase and retracted quickly to a lesser puncturing depth. Subsequently, the lancing element is retracted slower than during the first retraction movement and the distance retracted during the second retraction is shorter than the first retraction movement. During the second retraction movement, body fluid is collected in a collection phase by a capillary structure of the lancing element. Contact between the lancing element and the body fluid is detected after the forward phase at the beginning and the end of a waiting period.

Method and device for the extraction of a body fluid

A device for sampling, transporting and/or disposal of fluid media in the nl and &#x3bc;l-range comprises a substrate with and open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.

Growing community of inventors

Cham, Switzerland

Stephan Korner