Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit Und Umwelt

Ludwig-Maximilians-Universitat München

Universitat Der Bundeswehr Munchen

Stephan Kellnberger

Vasilis Ntziachristos

Günther Dollinger

Katia Parodi

Pouyan Mohajerani

Walter Assmann

The invention relates to a device () and a corresponding method for thermoacoustic sensing, in particular thermoacoustic imaging, the device () comprising: a) an irradiation unit () configured to generate electromagnetic and/or particle energy exhibiting a first modulation, the first modulation comprising at least one frequency and to continuously emit the energy towards a target (), whereby acoustic waves are continuously generated in the target, the acoustic waves exhibiting a second modulation, the second modulation comprising the at least one frequency and/or a harmonic frequency of the at least one frequency; b) a detection unit () configured to simultaneously detect the acoustic waves exhibiting the second modulation while the energy exhibiting the first modulation is being continuously emitted towards the target (); and c) a processing unit () configured to determine at least one thermoacoustic value of an amplitude and/or a phase of the second modulation of the acoustic waves at the at least one frequency and/or at a harmonic frequency of the at least one frequency. The invention allows for fast and economic thermoacoustic sensing, in particular imaging of a region of interest of an object.

Device and method for frequency-domain thermoacoustic sensing

Disclosed is a method of determining information regarding the location of energy deposition of an ion beam, in particular a proton beam, in an absorptive medium, in particular in the tissue of a patient undergoing radiation therapy, comprising the following steps:

Method and apparatus for determining an energy deposition of an ion beam

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Kuenzing, Germany

Stephan Kellnberger