Basf Se Corporation

Wintershall Holding Gmbh

Other

Basf Aktiengesellschaft

Solenis Technologies, L.p.

Solenis Technologies Cayman, L.p.

Stephan Freyer

Matthias Boy

Wolfgang Siegel

Oskar Zelder

Peter Oedman

Stefanie Demming

Markus Pompejus

Kai-Uwe Baldenius

Gabriele Iffland

Rajan Hollmann

Jens Wittenberg

Suman Thotla

Markus Lohscheidt

Julia Kristiane Schmidt

Matthias Kleiner

Juergen Daeuwel

Alfred Oftring

Eckhard Stroefer

Klemens Massonne

Oemer Uensal

Martin Ernst

Alois Kindler

Christopher Koradin

Claus Bollschweiler

Gerhard Schulz

Ansgar Gereon Altenhoff

Veit Stegmann

Andrea Herold

Hartwig Schroeder

Martin Fiene

Hartwig Schroder

Manfred Ehresmann

Mari Granström

Wolfgang Staffel

Thomas Letzelter

Benjamin Wenzke

Franz Weber

Jörg Therre

Giovanni D'Andola

Kerstin Hage

Julia Brodersen

Michael Guenter Braun

Tobias Käppler

Michael Budde

Yvonne Hoelzl

Bernd Leonhardt

Andreas Pletsch

Melanie Bonnekessel

Kathrin Wissel-Stoll

Till Christian Brueggemann

Burkhard Ernst

Thomas Kaeding

Christian Fleck

Katrin Treier-Marxen

Andreas Schaedler

Tillmann Faust

Ömer Ünsal

Sascha Rollie

Tim Balensiefer

Florian Lehr

Hans-Juergen Lang

Sebastian Schoof

Michael Kiefer

Michael Helmut Kopf

Karin Schein-Albrecht

Christian Brueggemann

Carsten Schwalb

Sebastian Briechle

Andrea Hlubek

Foppe Visser

Hansjörg Rettenmaier

Gunter Steigelmann

Peter Odman

Tobias Kappler

Michael Braun

Tobias Kaeppler

Petra SPRÖTE

Peter ÖDman

Michael Günter Braun

Hartwig SCHRÖDER

Till Christian BRÜGGEMANN

The present invention relates to a method for recovering a protein of interest from a fermentation broth by adding a salt of a divalent cation and increasing the pH.

Method of recovering a protein from fermentation broth using a divalent cation

The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.

Method for producing an amide

The presently claimed invention is directed to a method for the preparation of an aqueous solution comprising at least one beta-glucan comprising at least the steps of a) fermentation of at least one fungal strain in an a fermentation broth, b) addition of at least one acid to the fermentation broth to adjust the pH to a value in the range of &#x2265;2.0 to &#x2264;4.0 and c) filtration of the fermentation broth to obtain an aqueous solution comprising the at least one beta-glucan and at least one beta-glucan that is obtained by this method.

Method for preparing an aqueous solution of beta-glucan

The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.

Method for preparing an aqueous acrylamide solution having a low acrylic acid concentration

The invention pertains to processes to produce dry biomass of pyripyropene producer organisms, processes to obtain pyripyropenes from such dry biomass, as well as to processes to produce compounds of Formula III and/or Formula IV and/or Formula V from the pyripyropenes obtained from the dry biomass. The invention does further pertain to the dry biomass itself, as well as processes using said dry biomass to obtain pyripyropenes for the production of compounds of Formula III and/or Formula IV and/or Formula V, including processes using said dry biomass to obtain pyripyropenes or compounds of Formula III and/or Formula IV and/or Formula V in order to produce pest control compositions, in particular insecticides, comprising such compounds.

Production of pyripyropenes from dry biomass

The invention relates to a process for continuously preparing di-C-alkyl succinates by reacting succinic acid with an C-alkanol in the presence of a fixed-bed heterogeneous acidic esterification catalyst in a tubular reactor at a temperature in the range of from 60 to 100&#xb0; C., wherein a mixture, comprising succinic acid, C-alkanol, mono-C-alkyl succinate, di-C-alkyl succinate and water, is formed in a mixing stage and fed to the entrance of the tubular reactor, and wherein 5 to 75% of the outlet flow rate of the tubular reactor are recycled directly to the mixing stage as a recycle stream, and the molar ratio of C-alkanol to succinic acid added to the mixing zone, and not including the C-alkanol and succinic acid at the recycle stream, being in the range of from 2.0 to 9.5. The invention furthermore relates to a process for separating the reactor effluent of an esterification of succinic acid with an C-alkanol to give di-C1-3-alkyl succinates by distillation, wherein the separation is performed in a divided wall column in which C-alkanol and water are removed in a top draw of the column, di-C-alkyl succinate is removed in a side draw of the column, and wherein mono-C-alkyl succinate and succinic acid are removed in a bottom draw of the column.

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The invention relates to a process for continuously preparing di-C-alkyl succinates by reacting succinic acid with an C-alkanol in the presence of a fixed-bed heterogeneous acidic esterification catalyst in a tubular reactor at a temperature in the range of from 60 to 100&#xb0; C., wherein a mixture, comprising succinic acid, C-alkanol, mono-C-alkyl succinate, di-C-alkyl succinate and water, is formed in a mixing stage and fed to the entrance of the tubular reactor, and wherein 5 to 75% of the outlet flow rate of the tubular reactor are recycled directly to the mixing stage as a recycle stream, and the molar ratio of C-alkanol to succinic acid added to the mixing zone, and not including the C-alkanol and succinic acid at the recycle stream, being in the range of from 2.0 to 9.5. The invention furthermore relates to a process for separating the reactor effluent of an esterification of succinic acid with an C-alkanol to give di-C-alkyl succinates by distillation, wherein the separation is performed in a divided wall column in which C-alkanol and water are removed in a top draw of the column, di-C-alkyl succinate is removed in a side draw of the column, and wherein mono-C-alkyl succinate and succinic acid are removed in a bottom draw of the column.

A two-stage process for mineral oil production from mineral oil deposits with a deposit temperature of more than 70&#xb0; C. and a salinity of 20 000 ppm to 350 000 ppm, in which an aqueous formulation comprising at least one glucan with a &#x3b2;-1,3-glycosidically linked main chain, and side groups &#x3b2;-1,6-glycosidically bonded thereto and having a weight-average molecular weight Mof 1.5*10to 25*10g/mol, are injected into a mineral oil deposit through at least one injection borehole and crude oil is withdrawn from the deposit through at least one production borehole. The aqueous formulation is prepared in two stages, by first preparing an aqueous concentrate of the glucan, and diluting the concentrate on site with water to the use concentration.

Process for mineral oil production from mineral oil deposits with high deposit temperature

The invention relates to a process for the production of at least one microbial metabolite having at least 3 carbon atoms or at least 2 carbon atoms and at least 1 nitrogen atom by means of sugar-based microbial fermentation, comprising:

Fermentative production of fine chemicals

The present invention is directed to a method for coating a sheet-like cellulose containing material by applying a composition comprising at least one glucan (G), which has a &#x3b2;(beta)-1,3-glycosidically linked main chain and at least one side group having a &#x3b2;(beta)-1,6-glycosidic bond to the main chain, particularly Schizophyllan, and at least one solvent (S), particularly a ionic liquid, on the surface of the sheet-like material.

Method for the coating of a cellulose material by using a glucan

The present invention relates to a method for manufacturing an aqueous glucose solution from the starch components of Triticeae grains, for example from rye, triticale or in particular wheat grains. The invention also relates to a glucose-based fermentation method for manufacturing organic compounds in which the glucose manufactured for fermentation is produced from the starch components of Triticeae grains by way of a method according to the invention.

Method for manufacturing an aqueous glucose solution from plants of the Triticeae species

A process for the fermentative production of at least one organic compound having at least 3 C atoms or having at least 2 C atoms and at least one 1 N atom, comprising the following steps:

Fermentative production of organic compounds

The invention relates to a method for producing at least one organic compound comprising at least 3 C-atoms or at least 2 C-atoms and at least 1 N-atom by fermentation. Said method comprises the following steps: i) a starch source is ground in order to obtain a grinding material which contains at least one part of the non-starch containing solid components of the starch source; ii) the grinding material is suspended in an aqueous liquid in an amount such that the dry mass content in the suspension is at least 45 wt. %, iii) the starch component is hydrolysed in the grinding material by liquefying and optionally, subsequently, sweetening, in order to obtain an aqueous medium M, which contains the hydrolysed starch components and at least one part of the non-starch containing solid components of the starch source, is obtained; and iv) the aqueous substance M obtained in step iii) is used for fermentation in order to cultivate a micro-organism which is capable of over-producing the organic compound; the suspension obtained in step ii) is heated in step iii) by introducing vapor into the suspension, in order to obtain temperatures greater than the pasting temperature of the starch obtained in the grinding materials.

Process for the production of at least one organic compound having at least 3 C atoms or having at least 2 C atoms and at least 1 N atom by fermentation. In particular, the process comprises milling a starch feedstock, thus obtaining a millbase which comprises at least part of the nonstarchy solid constituents of the starch feedstock; suspending the millbase in an aqueous liquid and liquefying the millbase present in the aqueous liquid in the presence of at least one starch-liquefying enzyme, obtaining an aqueous dextrin-containing medium (1) which comprises at least a part of the nonstarchy solid constituents of the starch feedstock; and using the aqueous dextrin-containing medium (1) in a fermentation for culturing a microorganism which is capable of overproducing the organic compound; wherein enzymes which hydrolyze the dextrins to monosaccharides are being added in an amount of less than 0.001% by weight based on the total weight of the starch feedstock employed, or not at all.

Fermentative production of organic compounds using substances containing dextrin

The present invention relates to 5-isopropyl-3-aminomethyl-2-methyl-1-aminocyclohexane (carvonediamine) and to a process for preparation thereof by a) reacting carvone with hydrogen cyanide, b) then reacting the carvonenitrile obtained in stage a) with ammonia in the presence of an imine formation catalyst and c) then reacting the carvonenitrile imine-containing reaction mixture obtained in stage b) with hydrogen and ammonia over hydrogenation catalysts. The present invention further relates to the use of carvonediamine as a hardener for epoxy resins, as an intermediate in the preparation of diisocyanates, as a starter in the preparation of polyetherols and/or as a monomer for polyamide preparation.

5-isopropyl-3-aminomethyl-2-methyl-1-amino-cyclohexane (carvone diamine), and method for the production thereof

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Neustadt, Germany

Stephan Freyer