Bayer Aktiengesellschaft

Bayer Intellectual Property Gmbh

Bayer Pharma Aktiengesellschaft

Bayer Schering Pharma Aktiengellschaft

Stephan Bartel

Rainer Endermann

Uwe Petersen

Thomas Schenke

Karl G Metzger

Thomas Jaetsch

Klaus-Dieter Bremm

Dieter Habich

Bernd Riedl

Andreas Stolle

Hein-Peter Kroll

Martin Ruppelt

Johannes-Peter Stasch

Karl-Heinz Schlemmer

Frank Wunder

Thomas Rölle

Wahed Ahmed Moradi

Andreas Krebs

Klaus Schaller

Michael Hahn

Klaus Dieter Bremm

Harald Labischinski

Walter Guarnieri

Hans-Otto Werling

Andreas Knorr

Thomas Himmler

Bernd Baasner

Michael Matzke

Thomas Philipps

Eva-Maria Becker

Burkhard Mielke

Klaus Grohe

Hermann Hagemann

Dieter Lang

Michael Schriewer

Franz Kunisch

Hanno Wild

Karl-Georg Metzger

Klaus Münter

Uwe Peterson

Thomas Sch&eacute;nke

The present application relates to novel dicarboxylic acid derivatives, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

Dicarboxylic acid derivatives and their use

The present application relates to novel tetrazole derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

Tetrazole derivatives and their use for the treatment of cardiovascular diseases

The present application relates to novel difluorophenol derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

Difluorophenol derivatives and their use

The invention relates to biphenyl compounds of formula (I): wherein U, V and W together form a group of the formula *&#x2014;CH&#x2550;CH&#x2014;CH&#x3c;, *&#x2014;CH&#x2014;CH&#x2014;CH&#x3c; or *&#x2014;CH&#x2014;CH&#x2014;N&#x3c;, in which * means the point of linkage to the phenyl ring; A is O or CH; and D, E, X, Y, Z, R, R, o, n, and p are as defined in the specification. The invention also relates to pharmaceutical compositions of the compound of the compounds. The compounds and pharmaceutical compositions of the invention can be used in the treatment or prevention of cardiovascular disorders.

Biphenyl compounds useful in the treatment or prevention of cardiovascular disorders

The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives, which are substituted in the 7-position by a 2-oxa-5,8-diazabicyclo&lsqb;4.3.0&rsqb;-non-8-yl) radical, and their pharmaceutically utilizable hydrates and/or salts for the therapy of infections and the gastroduodenal disorders associated therewith.

USE OF 7-(2-OXA-5,8-DIAZABICYLCO&lsqb;4.3.0&rsqb;NON-8-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDON CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF HELIOBACTER PYLORI INFECTIONS AND ASSOCIATED GASTRODUODENAL DISEASES

The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in position 7 by a 1-aminomethyl-2-oxa-7-azabicyclo&lsqb;3.3.0&rsqb;oct-7-yl radical, and of their salts for the therapy of,infections and associated gastroduodenal disorders.

Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo&lsqb;3.3.0&rsqb;oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith

Use of 7-(2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-quinolone carboxylic

The invention relates to heteroatom-containing benzocyclopentaneoxazolidinones, to processes for their preparation and their use as medicaments, especially as antibacterial medicaments.

Heteroatom-containing benzocyclopentane-oxazolidinones

The invention relates to intermediate compounds for preparing novel quinolone derivatives- and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.

7-isoindolinyl-quinolone derivatives and 7-isoindolinyl-naphthyridone

The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a tricyclic amine radical, their salts, processes for their preparation and antibacterial compositions comprising these compounds.

Quinolone- and naphthyridonecarboxylic acid derivatives

The invention relates to novel heteroaryl-oxazolidinones of the general formula (I): ##STR1## in which the substituents are as defined in the description, to processes for their preparation and to their use as drugs, especially as antibacterial drugs.

Heteroaryl-oxazolidinones

The present invention relates to 2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.

2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones

The present invention relates to new pyrido-fused thienyl- and furanyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.

Pyrido-fused thienyl- and furanyl-oxazolidinones

The invention relates to novel 1,6-naphthyridonecarboxylic acid derivatives, to processes for their preparation, to antibacterial compositions and feed additives in which they are present, and to novel intermediates for the preparation of these active compounds.

1,6-naphthyridonecarboxylic acid derivatives

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Bergisch Gladbach, Germany

Stephan Bartel