Zambon Group S.p.a.

Italfarmaco Sud S.p.a.

Chem Spa

Stefano Servi

Lorenzo De Ferra

Claudio Fuganti

Angelo Gentile

Luca Ghirotto

Claudio Giordano

Pietro Massardo

Oreste Piccolo

Mauro Anibaldi

Daniele Scorretti

Claudi O Giordano

Ezio Fasoli

Process for preparing lysophosphatidylcholine by selective monoacylation of glycerophosphorylcholine (1), in the presence of an acylating agent and of a dialkyltin derivative, according to the following diagram:  The process is particularly simple and has high overall yields.

Process for preparing lysophosphatidylcholine

Process for the preparation of intermediates useful for the synthesis for benzothiazepines

The invention relates to a process for the preparation of phosphatidylserines by reacting racemic or enantiomerically pure serine, preferably (L)-serine, with natural phosphatides, such as soybean or egg lecithin, or with synthetic phosphatides, in the presence of a phospholipase D, having transphosphatidylating activity, in an aqueous/organic diphasic system.

Process for the industrial preparation of phosphatidylserine

A process for the preparation of the compounds of formula ##STR1## (wherein R has the meanings reported in the specification) by enzymatic transesterification of enantiomeric mixtures is described. These compounds are intermediates useful in the synthesis of Diltiazem.

Process for the preparation of intermediates useful for the synthesis of

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Milan, Italy

Stefano Servi