Zambon Group S.p.a.

Sanofi-aventis

Zambon Group S.a.

Stefano Romagnano

Franco Pellacini

Francesco Santangelo

Gabriele Pietro Norcini

Claudio Semeraro

Daniela Botta

Mario Fantucci

Enrico Albini

Giovanna Schioppacassi

Roberto Cecchi

Tiziano Croci

Philippe Bovy

Ermanno Moriggi

Domenico Ungheri

Laura Barzaghi

Lorenzo Pradella

The invention relates to phenoxypropanolamines, to pharmaceutical compositions containing them, to processes for preparing them, and to the method of use thereof in the treatment of diseases that are improved by beta-3 agonist action.

Propanolaminotetralines, preparation thereof and compositions containing same

The present invention discloses an erythromycin derivative with antibiotic activity and pharmaceutically acceptable salts thereof, a process for their preparation and pharmaceutical compositions containing them as active principle.

Erythromycin derivative with antibiotic activity

3&prime;-Des-dimethylamino-9-oxyimino macrolides of formula (I) endowed with anti-inflammatory activity and their pharmaceutical use are described.

Macrolides with anti-inflammatory activity

Thiol derivatives with metallopeptidase (ACE/NEP) inhibitory activity

Compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula I are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.

Mercapto acyl aminoacid derivatives endowed with dual ACE-NEP inhibitory

Thiol derivatives with metallopeptidase inhibitory activity

Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity

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Buccinasco, Italy

Stefano Romagnano