A. Menarini Industrie Farmaceutiche Riunite S.r.l.

Malesci Istituto Farmacobiologico S.p.a.

A. Menarini S.a.s.

Menarini Ricerche S.p.a.

Berlin-chemie Ag

Menarini Richerche S.p.a.

A. Menarini Industrie Farmaceutiche Reiunite S.r.l.

Stefano Manzini

Federico Maria Arcamone

Paolo Lombardi

Alessandro Sisto

Edoardo Potier

Carlo Alberto Maggi

Christopher Fincham

Aldo Salimbeni

Damiano Turozzi

Vittorio Pestellini

Alberto Meli

Mario Ghelardoni

Danilo Giannotti

Alessandro Giolitti

Davide Poma

Mauro Fedi

Graziano Bonacchi

Carla Bacciarelli

Guglielmo Grimaldi

Orenzo Agostini

A new process for the preparation of bicyclic peptide compounds Formula (I) in high yields of high purity, useful as intermediates for preparing compounds with pharmacological activity, is described. 

Process for the preparation of bicyclic peptide compounds

Process of preparing (E)-5-(2-bromovynyl)-2'-deoxyuridine (Brivudine) characterized in that halogen-free solvent selected form esters or cyclic ethers are used in the bromination step of 5-ethyl-2&#x2032;-deoxyuridine diacylate. The use of solvents is advantageous in respect of toxicity, discharge costs and environment protection.

Process for the preparation of (e)-5-(2-bromovinyl)-2'-deoxyuridine

The present invention refers to tachykinins antagonists of general formula (I) ##STR1## their preparation and pharmaceutical compositions containing them.

Tachykinins antagonists

A description is given of tachykinin receptor antagonists having general formula (I) ##STR1## their preparation and use in pharmaceutical formulations.

Tachykinin antagonists

Tachyquinine antagonists, their preparation and use in pharmaceutical

1-7 disubstituted xanthine derivatives having antiasthmatic activity,

The invention comprises: a derivative of 1-alkylamine-3-[4(p-alkyloxy-benzamide)phenoxy]-2-propanol of general formula I: ##STR1## where R.sub.1 is a linear or branched alkyl chain with 1 to 8 carbon atoms included, an alkenyl chain with 2 to 8 carbon atoms included, or an arylalkyl chain with 7 to 10 carbon atoms included, and R is a linear or branched alkyl group with 1 to 8 carbon atoms included;

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Stefano Manzini