Autifony Therapeutics Limited

Glaxo Group Limited

Stefano Fontana

Giuseppe Alvaro

Agostino Marasco

Dieter Hamprecht

Charles Large

Anne Decor

Barbara Bertani

Alessandra Pasquarello

Susanna Cremonesi

Anne Décor

The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.

Imidazolidinedione derivatives

The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizophrenia, substance abuse disorders, sleep disorders or epilepsy.

The present invention relates to novel compounds of formula (I) or a salt thereof: wherein

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Verona, Italy

Stefano Fontana