Biomedica Foscama Industria Chimico-farmaceutica

Biomedica Foscama Industrial Chimico-farmaceutica, S.p.a.

Stefano Ceccarelli

Mario Brufani

Romolo Scuri

Agnese Paesano

Patrizia Giannetti

Sergio Zanarella

Zanarella Sergio

Patrizia DeVellis

Magnante Francesco

Alessandra D'Alessandro

Patrizia De Vellis

Maria Altobelli

Sergio Zanarcella

Imidazo[1,2-a]quinoxalin-4-amines active as adenosine antagonists,

A process is described for preparing octahydro trisodium salt of fructose 1,6-diphosphate starting from an aqueous solution at an acid pH of D-fructose 1,6-diphosphate, to which a suitable amount of acetone is added. The reactive mixture is crystallized and filtered to obtain the desired product, which is finally dried.

Process for obtaining octahydro trisodium salt of fructose

There are described 8-(1-aminocycloalkyl)-1,3-dialckylxantaine, their derivatives and their salts with adenosine antagonist activity. A process for the preparation of said compounds and pharmaceutical compositions containing them as antidepressant, nootropic and psychostimolant drugs are also described.

8-(1-aminocycloalkyl)-1,3-dialkylxanthine derivatives, preparation

The herein-described invention concerns new 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofuranes 2-(RS)-substituted, the synthesis procedure and the relative therapeutic use as antioxidizing and radical-scavenging pharmaceuticals with mucoregulation and anti-ischemic properties.

2,3-dihydro-5-oxy-4,6,7-trimethylbenzofurans 2-(RS)-substituted, useful

The present invention relates to (RS)-2-(2,3-dihydro-5-hydroxy-4-,6-trimethylbenozfuranyl) acetic acids and 2-(2,3-dihydro-5-acyloxy-4-,6,7-trimethylbenzofuranyl) acetic acids and esters thereof, the process for producing them and their relevant therapeutical use as mucoregulators and antio-ischemic agents.

Production of (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl)

The present invention relates to (RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acids and 2-(2,3-dihydro-5-acyloxy-4,6,7-trimethylbenzofuranyl) acetic acids and esters thereof, the process for producing them and their relevant therapeutical use as mucoregulators and antiischemic agents.

(RS)-2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acids

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Frosinone, Italy

Stefano Ceccarelli