Ric Investments, Inc.

Stefanida K Blake

Erik Kurt Witt

Stephen Dalton Pittman

Peter Chi Fai Ho

Michael Edward Colbaugh

Zachary Dean Paul

Smita Garde

Steven B Radney

Stefanie Lattner

Charles Thomas

Benjamin Alfred Giovannelli

Leonardo A Baloa

Mark DiMatteo

Michael Cessna

Patrick Devinney

Jacobo D Reif

David P White

Manuel Laura

Jacobo Reif

Stephen D;c/o Respironics Inc Pittman

A system that determines one or more sleep phenotyping parameters of a subject. In one embodiment, the system comprises a sleep sensor, a stimulus generator, and a processor. The sleep sensor generates signals that convey information related to the physiological functions that indicate the sleep stage of the subject. The stimulus generator provides a stimulus to the subject that enables information related to the sleep phenotyping parameters to be determined. The processor receives the signals generated by the sleep sensor and is in operative communication with the stimulus generator. The processor (i) determines, based on the signals received from the sleep sensor, whether a trigger condition related to the current sleep stage of the subject is satisfied, (ii) controls the stimulus generator to provide the stimulus to the subject if the trigger condition is satisfied, and (iii) quantifies the response of the subject to the stimulus.

Automated sleep phenotyping

A therapy system adapted to treat a patient's ventilatory instability using a ventilatory therapy, a gas modulation therapy, or both. The algorithm implemented by the therapy system monitors the ventilatory instability, such as Cheyne Stokes Respiration (CSR), mixed apneas, CPAP emergent apneas, and complex sleep disordered breathing (CSDB) and treats the ventilatory instability. The algorithm also determine a reference point with respect to the ventilatory instability. The therapy delivery system initiate the treatment based on the reference point.

System and method for treating ventilatory instability

Apparatus for the non-invasive and specific activation of the vestibular system in a patient. Preferred embodiments of the present invention allow for the placement of a stimulating electrode in the ear canal while providing a firm and comfortable coupling with the patient. The stimulating electrode is a deformable material that contacts the skin in the ear canal. A stimulating device operates in cooperation with the stimulating electrode to generate a stimulation waveform for the stimulation of the vestibular system.

Vestibular system stimulation apparatus

A system is provided for delivering a flow of breathing gas to an airway of a patient. The system includes a pressurizing flow module that generates a pressurized flow of breathing gas and a patient circuit coupled to the pressurizing flow module configured to communicate the flow of breathing gas to an airway of a patient. The system includes a sensor for monitoring a characteristic of a breathing pattern of the patient a controller that communicates with the sensor configured to increase a fraction of inspired carbon dioxide if the characteristic exceeds an upper threshold value and to provide servo-ventilation if the characteristic is less than a lower threshold value. The upper threshold value and the lower threshold value are changed based on the monitored characteristic of the breathing pattern of the patient.

Ventilatory control system

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Jamaica Plain, MA, United States of America

Stefanida K Blake