Fresenius Medical Care Deutschland Gmbh

Stefania Bruno

Giovanni Camussi

Ciro Tetta

Maria Beatriz Herrera Sanchez

Valentina Fonsato

Benedetta Bussolati

The invention is in the field of therapeutic treatment of tumors. The inventors have found that microvesicles derived from adult stem cells exert a remarkable anti-tumor effect when administered to a patient affected by a tumor disease. Preferred microvesicles are derived from a bone marrow-mesenchymal stem cell, a glomerular mesenchymal stem cell or a non-oval liver stem cell.

Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease

Microvesicles (MVS) derived from adult stem cells for use in the therapeutic treatment of a tumor disease

The invention relates to an isolated multipotent glomerular mesenchymal stem cell derived from adult human kidney (hGL-MSC), which is characterized by the marker profile CD133, CD146, CD34and CD105. A method of preparing the hGL-MSC of the invention form decapsulated glomeruli is also disclosed, as well as the uses of the hGL-MSC of the invention in the regenerative treatment of the kidney, particularly for the treatment of injuries or diseases affecting renal glomeruli.

Isolated multipotent mesenchymal stem cell from human adult glomeruli (HGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney

Growing community of inventors

Pinerolo, Italy

Stefania Bruno