Clondiag Chip Technologies Gmbh

Stefan W&ouml;lfl

Torsten Schulz

Eugen Ermantraut

Johann Michael K&ouml;hler

Klaus Wohlfart

The present invention relates to novel thin layers for microsystem techniques and microstructuring. It is an object of the invention to provide thin layers which can be manufactured under less problems and more economically than the previous conventional layers, and which permit the use of existing technologies for microstructuring. The object is realized in that the thin layer is formed of an enzymatically degradable biopolymer in a range of layer thicknesses of from 30 nm to 3 &mgr;m. Biopolymeric thin layers manufactured according to the invention permit their application, after a respective structurizing, as test assays or in setting up substance libraries.

Kind of thin films for microsystem technology and microstructuring and their use

The invention relates to a method for producing structured, self-organized molecular monolayers of individual molecular species. The invention is preferably used to create solid-phase bonded substance libraries. To this end, a) a substrate ( ) suitable for the first monolayer is provided; b) a microstructured polymer mask ( ) having openings is applied to the subtrate ( ) at least once in a defined direction. Said polymer mask ( ) is sufficiently thin and flexible for it to adhere to the substrate ( ) by adhesion, and the material selected for the polymer mask ( ) is chemically stable; c) the sandwich constituted by the substrate ( ) and polymer mask ( ) is flooded with a first agent corresponding to the intended use, so as to create at least one first molecular monolayer in the areas defined by the mask openings; c1) depending on the monolayer structure to be created step c) is repeated using the first agent or one or more additional agents; and d) after carrying out the step described in c) or the steps described in c) and c1), the polymer mask is pulled off after modification of the substrate surface areas which were left uncovered by the mask openings and were subjected to the agent or agents.

Growing community of inventors

Jena, Germany

Stefan Wölfl

Growing community of inventors

Jena, Germany

Stefan W&ouml;lfl

Stefan Wölfl