Roche Molecular Systems, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Stefan Vollenweider

Sven Ebert

Paul Federer

Thomas Schlaubitz

Pius Hermann

Urs Wittenwiler

Philipp Zeller

A device for the thermal treatment of test samples is presented. The device comprises a sample holder and one or more thermoelectric elements which are in thermal contact with the sample holder. The sample holder comprises at least two holding positions configured to hold test sample consumables. The sample holder comprises an internal working fluid and a hollow body with an inner bottom surface and an inner top surface connected to each other with a pillar. The pillar extends along a vertical axis perpendicular to the inner bottom surface and substantially in the middle of the distance between the at least two holding positions. A laboratory instrument and a method for the thermal treatment of test samples is also presented.

Device for the thermal treatment of test samples

A method to monitor and control the temperature of a sample holder of a laboratory instrument during execution of a temperature profile on the sample holder is presented. The laboratory instrument comprises a sample holder with high temperature uniformity and at least three identical temperature sensors. The measured actual temperatures of the sample holder are processed in order to determine if the execution of the temperature profile should be continued or aborted. Furthermore, temperature sensors which measure actual temperatures that do not fulfil certain requirements are excluded from further monitoring and controlling the temperature of a sample holder.

Method to monitor and control the temperature of a sample holder of a laboratory instrument

An assembly comprising a sample block, a heat sink and at least one electrodeposited thermoelectric element is disclosed. Further, an instrument and a method for performing a temperature-dependent reaction are disclosed.

Assembly, instrument for performing a temperature-dependent reaction and method for performing a temperature-dependent reaction in an assembly

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Sins, Switzerland

Stefan Vollenweider