Basf Aktiengesellschaft

Stefan Stahl

Wolfgang Harder

Arthur Hoehn

Thomas Kuekenhoehner

Volker Maywald

Peter Muenster

Preparation of 5-cyanovalerates (I) by the carbonylation of a 1-cyanobutene with carbon monoxide and an alkanol (II) corresponding to the ester radical at an elevated temperature and under superatmospheric pressure in the presence of a cobalt catalyst as well as in the presence of an activating solvent, in which the activating solvent used is an effective amount of a urea of the formula IIIc

Preparation of 5-cyanovalerates

Preparation of 5-cyanovalerates (I) by the carbonylation of a 1-cyanobutene with carbon monoxide and an alkanol (II) corresponding to the ester radical at an elevated temperature and under superatmospheric pressure in the presence of a cobalt catalyst as well as in the presence of an activating solvent, in which the activating solvent used is an effective amount of a carbonic diester, a carbamate, or a urea of the general formula IIIa, IIIb, or IIIc

A process for preparing isoxazole-3,4-dicarboxylic acid derivatives of the formula I ##STR1## where R.sup.1 is hydrogen, alkyl, cycloalkyl or phenyl, or a 5- to 6-membered heterocyclic radical, and the organic radicals can have substituents which are inert under the reaction conditions;

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Worms, Germany

Stefan Stahl