Conaris Research Institute Ag

Christian-albrechts-universitat Zu Kiel

Universitätsklinikum Schleswig-Holstein

Stefan Schreiber

Stefan Rose-John

Dirk Seegert

Georg Wätzig

Nikolaus Rahaus

Georg H Watzig

Andre Franke

Mark Ellrichmann

Daniela Fangmann

Jörg Knipp

Karin Schwarz

Julia Keppler

Almut Nebel

Philip Rosenstiel

Eva-Maria Theismann

Friederike Flachsbart

Matthias Laudes

Andreas Till

A method is provided for detecting an increased susceptibility to ulcerative colitis by determining the presence of a polymorphism at position 256 of the nucleotide sequence of rs3024505 in which C is substituted by T or the presence of a polymorphism at position 501 of the nucleotide sequence of rs12612347 in which G is substituted by A.

Method for identifying an increased susceptibility to ulcerative colitis

A polypeptide-dimer comprising two soluble gp130 molecules is described, wherein at least one of said soluble gp130 molecules is covalently linked to polyethylene glycol. Furthermore, a pharmaceutical composition containing said dimer and various medical uses are described.

PEGylated soluble GP130-dimers useful as a medicament

PEGylated soluble gp130-dimers useful as a medicament

Growing community of inventors

Kiel, Germany

Stefan Schreiber