Biotronik Se Co. Kg

Biotronik Crm Patent Ag

Stefan Paule

Michael Lippert

Gerald Czygan

Frank Becker

Thomas Doerr

Olaf Skerl

Ulrich Busch

Torsten Radtke

Sergey Ershov

Thomas Dörr

Peter Schneider

Thomas Kraemer

Michael Vollkron

Albrecht Urbaszek

Bernhard Fahn

Heinrich Reinke

A programming device for programming an implantable medical device for stimulating a human or animal heart, wherein the following steps are performed: a) allowing to select one of at least two electrode lead configurations for stimulating a human or animal heart, wherein the at least two electrode lead configurations comprise a second electrode lead configuration in which at least one electrode lead is connected to an electrode lead port, the electrode lead port being configured to receive an electrode lead for stimulating a second cardiac region or detecting an electric signal at the second cardiac region, wherein the second cardiac region is a part of a ventricular conduction system of the heart, wherein the at least one electrode lead is intended to be implanted or is implanted in the second cardiac region; b) generating and releasing a notification signal if the second electrode lead configuration is selected.

Programming device for programming an implantable medical device for stimulating a human or animal heart

An implantable medical device for stimulating a human or animal heart. In operation, the device performs the following steps: a) sensing an atrial electric signal a the first detection unit; b) sensing an electric signal at the His bundle with a second detection unit upon termination of a first time period starting upon sensing the atrial electric signal with the first detection unit and/or starting upon applying a stimulation pulse, wherein the first time period lies in a range of from 10 ms to 100 ms; c) classifying the electric signal sensed with the second detection unit as His bundle activity signal or as ventricular activity signal.

Implantable medical device for stimulating the His bundle of a human or animal heart employing an improved distinction between atrial and ventricular signals detected at the His bundle

An implantable medical device for stimulating a human/animal heart, comprising a housing, a processor, a memory unit, a stimulation unit configured to stimulate the His bundle, and a detection unit configured to detect an electrical signal at the His bundle. The device performs: a) stimulating the His bundle with a stimulation pulse delivered by the stimulation unit; b) measuring an electric signal at the His bundle with the detection unit upon termination of a first period of time starting upon delivering of the stimulation pulse, wherein the first period of time is from 35 ms to 500 ms; c) measuring an impedance of the same heart with the detection unit upon termination of a second period of time starting upon delivering of the stimulation pulse, wherein the second period of time is equal to or longer than the first period of time and is from 50 ms to 500 ms.

Implantable medical device for stimulating the His bundle of a human or animal heart employing an adapted impedance measurement

An implantable medical device for stimulating a human/animal heart having a stimulation unit which stimulates the His bundle and a detection unit which detects an electrical signal at the His bundle. The device performs: a) determining a first value of a parameter of a first measuring pulse measured between a first electrode pole and a housing; b) determining a second value of the same parameter of a second measuring pulse measured between the first electrode pole and a second electrode pole; c) comparing the first and second values; d) determining, based on the comparing step, whether the first or second measuring pulses enables a higher available level control range of the analog-to-digital converter; e) measuring an impedance in a unipolar manner between the first electrode pole and the housing or in a bipolar manner between the first electrode pole and the second electrode pole depending on the determining step.

Implantable medical device for stimulating a human or animal heart employing an automatic choice between different impedance measuring modes

A monitoring device for a patient for predicting a cardiovascular anomaly and a method for operating a monitoring device is provided. Furthermore, an implantable electrotherapy device, such as an implantable cardiac pacemaker, an implantable cardioverter, or an implantable defibrillator, having a monitoring device are also provided. In an embodiment, the monitoring device acquires a value change of a hemodynamic parameter, which occurs as a result of a detected value change of a state parameter, for example, as a result of an activation or deactivation of a cardiac resynchronization therapy. By suitable evaluation of the value change of the hemodynamic parameter, the monitoring device can output an evaluation result signal which is indicative of an imminence of a cardiovascular anomaly, such as a cardiac decompensation, long beforehand and with high specificity.

Monitoring device and method for operating a monitoring device

A system which generates a warning signal in the event of looming pulmonary edema and/or looming decompensation. The system has an impedance detection unit for determining impedance values, which represent a transthoracic impedance course, and an impedance analysis unit (), which is connected to the impedance detection unit. The impedance analysis unit () is implemented to determine the degree of modulation for a particular impedance course detected by the impedance detection unit.

System and method for analyzing an impedance course

A monitoring apparatus having a signal input for signals representing measurement values of one or more physiological parameters, and an evaluation and processing unit connected to the signal input. The evaluation and processing unit is designed to select, or differently weight, individual values from the values received for further processing based on one or more criteria such that measurement values raising doubts as to the validity thereof are not selected or given a very low weighting.

Apparatus and method for processing physiological measurement values

An implantable medical device has an impedance or admittance determination unit, an alternating current or voltage source, a measuring unit, and an analysis unit which is connected to the alternating current or AC voltage source and the measuring unit to calculate an impedance value or an admittance value at different times. The impedance or admittance determination unit may generate measuring current having two different frequencies (preferably below 100 kHz), and the analysis unit may calculate pairs of impedance or admittance values which are chronologically assigned to one another for different frequencies of the measuring current, and calculate a value for a blood impedance or blood admittance component which is independent of the impedance of the body tissue surrounding a particular blood vessel, The analysis unit may also determine trends in this value over time as an indicator for a change of blood hematocrit value.

Implantable medical device for blood conductivity, blood impedance, and/or hematocrit measurement

A device for detecting the state of a heart on the basis of intracardial impedance measurement. The device has an impedance measuring unit, which has electrical terminals, configured to be electrically connected or to be connected to electrodes for delivering and detecting a current or voltage, and is implemented to ascertain an impedance on the basis of the dimension of the delivered current or voltage and the voltage drop caused by the current or the current caused by the voltage, as well as an analysis unit, which is connected to the impedance measuring unit and is implemented to derive a cardiac function parameter from a time curve of the impedance ascertained using the impedance measuring unit. The analysis unit analyzes the impedance curve assigned to a diastole and derives a cardiac function parameter characterizing the behavior of a heart during the diastole (filling phase of the ventricle).

Device for determining cardiac function parameters

A device is connected to electrode leads which performs intracardiac impedance measurements, conducts a transient pacing protocol, analyses the impedance measurements, and generates an LV lead position quality factor. The transient pacing protocol includes a repeated change ('transitions') between ventricular intrinsic rhythm and biventricular paced rhythm and may also include a variation of the atrioventricular delay (AVD) and/or the interventricular delay (VVD). The quality factor expresses the degree to which hemodynamic properties have improved due to BiV stimulation for the current LV lead position compared to intrinsic ventricular rhythm.

Growing community of inventors

Drosendorf, Germany

Stefan Paule