University of California

University College Dublin

National Research Council of Canada

Stefan Oscarson

John Vincent Fahy

Shaopeng Yuan

Stephen Carrington

Andrew Cox

Janelle Sauvageau

Wilfred Raymond

Lorenzo Guazzelli

Irina Gitlin

There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a dithiolsaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.

Dithiolsaccharide mucolytic agents and uses thereof

Processes for the preparation of phosphorylated heptose compounds are provided. Embodiments of the invention relate to the chemical synthesis of heptopyranose phosphate compounds. Also, embodiments of the invention relate to the use of compounds according to the invention in modulating an immune response in a subject.

Phosphorylated heptose compounds: process for their preparation and use

There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.

Thiosaccharide mucolytic agents

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Blackrock, Ireland

Stefan Oscarson