Medivir Ab

Stefan Lindström

Christer Sahlberg

Hans Kristian Wallberg

Christian Sund

Dmitry Antonov

Genaidy Kalyanov

Lourdes Salvador Odén

Lotta Naeslund

Hans Wallberg

A compound of the formula (Y): where; Ris O, S; Ris a nitrogen-containing heterocycle; Ris H, C-Calkyl; X is &#x2014;(CRR')-D-(CRR&#x2032;)&#x2014;; D is a bond, &#x2014;NR&#x2014;, &#x2014;O&#x2014;, &#x2014;S&#x2014;, &#x2014;S(&#x2550;O)&#x2014; or &#x2014;S(&#x2550;O)&#x2014;; n and m are independently 0, 1 or 2, Rand R&#x2032; are independently H, C-Calkyl, haloC-Calkyl, hydroxy, or Rand R&#x2032; together with their adjacent C atom is &#x2014;C(&#x2550;O)&#x2014;; Ris independently H, C-Calkyl; E is CH&#x2014;, &#x2014;CHOH&#x2014;, &#x2014;C(&#x2550;O)&#x2014;, &#x2014;NR&#x2014;, &#x2014;O&#x2014;, &#x2014;S&#x2014;, &#x2014;S(&#x2550;O)&#x2014;; n and m are independently 0, 1 or 2; p and q are independently 0, 1 or 2, where p+q&#x2266;2; Ris an optionally substituted carbocycle or heterocycle; Ris independently H, C-Calkyl, halo substituted C-Calkyl, hydroxy; have utility as HIV antivirals.

Non-nucleoside reverse transcriptase inhibitors

Intermediate compounds of non-nucleoside reverse transcriptase inhibitors

Growing community of inventors

Huddinge, Sweden

Stefan Lindström