Dräger Safety Ag&co. Kgaa

Merck Patent Gmbh

Stefan Lehmann

Dominik Joosten

Christian Ehrenreich

Wolfgang Bäther

David Maillard

Caroline Wern

Andreas Waechtler

Thorsten Vom Stein

Thomas Koppe

Luc Eberhardt

Björn Raupers

Wolfgang Bather

A gas sensorhas a measuring channelwith a gas inletand with a gas outlet, at least one receptor layer, a reference electrodeand a voltage-controlled analysis unit. The reference electrodeis capacitively coupled with the receptor layer. The reference electrodeis connected to the analysis unitin an electrically conductive manner. The receptor layeris formed in measuring channel. The measuring channelforms a dielectric layer between the receptor layerand the reference electrode. The receptor layerhas a supportand an analyte-binding layer. The present invention provides for the analyte-binding layerto be a self-assembling monolayer (SAM).

Gas sensor and gas-measuring device for detecting volatile organic compounds

A gas sensorhas a measuring channelwith a gas inletand with a gas outletat least one receptor layera reference electrodeand a voltage-controlled analysis unitThe reference electrodeis capacitively coupled with the receptor layerThe reference electrodeis connected to the analysis unitin an electrically conductive manner. The receptor layeris formed in measuring channelThe measuring channelforms a dielectric layer between the receptor layerand the reference electrodeThe receptor layerhas a supportand an analyte-binding layerThe present invention provides for the analyte-binding layerto be a self-assembling monolayer (SAM).

The present invention provides methods of preparing Praziquantel, in particular (R)-Praziquantel and analogues thereof in a stereoselective manner. One method involves asymmetric hydrogenation of the following intermediate compound and subsequent cyclization.

Method for the production of praziquantel and precursors thereof

A sensor unit () for detecting a gas is configured with a pressure-tight measuring channel (), with a gas inlet () for introducing the gas into the measuring channel, with a gas outlet () for removing the gas from the measuring channel, and with a pump unit () for evacuating the measuring channel. The measuring channel has a gas sensor () for detecting the gas and a heating unit () for heating the gas sensor. The sensor unit () is configured to be operated in a measuring mode and in a regeneration mode. The measuring channel () is evacuated and the gas sensor () is heated in the regeneration mode.

Gas-measuring device

The present invention relates to a gentle process for catalytic hydrogenation and to a process for the preparation of biotin using the hydrogenation step. The process according to the invention for the selective, catalytic hydrogenation of a C&#x2014;C double bond on a thiazole ring system having at least one functional group which can be converted into a salt under basic conditions is characterised in that the hydrogenation is carried out in a protic solvent is a pH&#x3e;7.

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Uetersen, Germany

Stefan Lehmann