Novartis Ag

Sensovation Ag

Stefan Bickert

Roland Hauck

Roger Biel

Peter Hagmann

Paul Anthony Hing

Hans W&ouml;rner

Roland Seibert

Olaf Rothe

The invention relates to a microscopy method for identifying target objects () having a predetermined optical property in material () to be analyzed. According to the invention, in a first step an overview field of view () of a microscope optical system () is directed to an overview region of a sample carrier () containing the material () to be analyzed, the material () to be analyzed is illuminated by an illumination unit (), which irradiates the sample carrier () from outside a field of view tube (), and is recorded by a camera (), the material () to be analyzed is optically analyzed for the optical property such that even a single target object () having the predetermined optical property is identified as such in the material () to be analyzed, in a subsequent second step a target field of view () of the microscope optical system () is aligned with a target region around the target object () using the known position of the target object (), and the identified target object () is analyzed in a differentiated manner for various additional optical properties.

Microscopy method for identifying biological target objects

The invention relates to a process for the production of a clamping means for clamping a component ( ) in a holder ( ), especially for the production of moulding tools for the manufacture of precision articles. Spring-action clamping elements ( ), for example tightening discs or clamping sleeves ( ), are inserted into a recess of the holder ( ) and final working thereof takes place in a position that corresponds to the subsequent position when the component ( ) to be clamped is clamped. With this process, very good centricity and coaxiality of the clamped components ( ) is achieved, whereby the manufacturing tolerances to be maintained for the individual components are not critical.

Moulding tool for the manufacture of precision articles, especially contact lenses

In an inspection module for inspecting optical parts ( ) for defects, especially contact lenses manufactured as injection-moulded parts, the optical parts ( ) are illuminated from one side and are observed from the opposite side by means of an image-resolving sensor ( ). The image data of the sensor ( ) are forwarded to image-processing means for identification of defects. To obtain a high throughput with a simple construction, a chain ( ) of liquid-filled vessels ( ) circulating in an endless line is provided. The endless line is passed in an inspection station ( ) between an illumination device ( ) and the image-resolving sensor ( ). Handling means in the form of grippers ( ) revolve with the vessels ( ), by means of which optical parts ( ) to be inspected can be introduced into the vessels ( ) at a position of the line upstream of the inspection station ( ) and the inspected parts can be taken out of the vessels ( ) at another position of the line.

Inspection module for inspecting optical parts for faults

The invention relates to an apparatus for the photo-initiated chemical cross-linking of material ( ). To form one or more mouldings the material is enclosed in an optically transparent mould ( ). The apparatus has at least one light source ( ), for example a pulsed UV light source by which the material ( ) can be acted upon by a light that triggers the cross-linking. The region to be cross-linked in the mould ( ) is determined at least partially by beam-delimiting elements ( ) between the light source ( ) and the mould ( ). That can be achieved by arranging between the light source ( ) and the mould ( ) a mask ( ) having transparent and non-transparent surface portions. The mask ( ) is then projected onto the material ( ) that is enclosed in the mould ( ) by projection optics ( ). The projection of the mask ( ) onto the material is effected in a telecentric beam path.

Apparatus for the photo-initiated chemical cross-linking of material

The invention relates to a process for the production of a clamping means for clamping a component (,) in a holder (,), especially for the production of moulding tools for the manufacture of precision articles. Spring-action clamping elements (,), for example tightening discs or clamping sleeves (,), are inserted into a recess of the holder (,) and final working thereof takes place in a position that corresponds to the subsequent position when the component (,) to be clamped is clamped. With this process, very good centricity and coaxiality of the clamped components (,) is achieved, whereby the manufacturing tolerances to be maintained for the individual components are not critical.

Growing community of inventors

Überlingen, Germany

Stefan Bickert