The General Hospital Corporation

Massachusetts Institute of Technology

Canon U.s.a., Inc.

Stefan A Carp

David Alan Boas

Maria Angela Franceschini

Dieter Manstein

Bruce R Rosen

Haruo Nakaji

Megan H Blackwell

Qianqian Fang

Mark Martino

Amir Y Sajjadi

Davide Tamborini

Erin Buckley

Oleg Shatrovoy

Pei-Yi Lin

An apparatus, including: a probe to interface with a surface of a tissue; a light source optically coupled to the probe, the light source directing light of at least 1000 nm into the tissue; a detector optically coupled to the probe, the detector to detect light based on scattering of light from the light source in the tissue, and the detector having a light sensitivity in a range of at least 1000 nm; a processor coupled to the detector, the processor to: receive a signal from the detector corresponding to the detected light from the light source, and determine a blood flow measurement from the region of interest using diffuse correlation spectroscopy based on the signal.

System and method for an optical blood flow measurement

The present disclosure provides systems and methods for characterizing and monitoring biological material. In one aspect, a method for characterizing biological material includes acquiring optical data associated with a biological material, and analyzing the optical data to determine optical properties of the biological tissue. The method also includes determining, using the optical properties, phase information corresponding to the biological material, and generating a report characterizing the biological tissue using at least the phase information.

Systems and methods for characterizing biological material using near-infrared spectroscopy

There is provided herewith an apparatus, probe, and method for the combination of near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). The apparatus, probe and method allow for the simultaneous detection of NIRS and DCS.

Near-infrared spectroscopy and diffuse correlation spectroscopy device and methods

A cancer screening method includes changing a compression state of selected tissue; and obtaining a signal indicative of a response of an optical property of the selected tissue in response to the change in the compression state.

Cancer detection by optical measurement of compression-induced transients

An exemplary apparatus can be provided to determine information regarding a sample(s), which can include, for example an arrangement(s) composed of, at least partially, a particular material in a predetermined area thereof, and including a light facilitating device that can be configured to provide or receive a light radiation(s) to or from the sample(s). The particular material can have a characteristic which can facilitate a sufficient amount of X-ray radiation to pass therethrough so as to generate an X-ray image(s). An X-ray absorption of the material can be at most about 10 times that of a &#xbc;&#x2033; acrylic plate. The light facilitating device can include a light transmitting configuration which can provide the light radiation(s) to the sample.

Optical fiber probe arrangement for use with X-ray mammography

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Charlestown, MA, United States of America

Stefan A Carp