Aratana Therapeutics, Inc.

Nv Remynd

Aratana Therapeutics Nv

Stefaan Wera

Johan Neyts

Erwin Blomsma

Nesya Goris

Ainola Billiet

Joeri Auwerx

Veerle Debeurme

Maryline Roe

Pascal Puig

Gerard Griffioen

Hein Roger Duhamel

Ellen Gommé

Nele Van Damme

Tom Van Dooren

Kristel Marie Edith Coupet

Tine Decruy

Marleen Lox

Ingrid Van Der Auwera

Ellen Gomme

Kristel Marie Coupet

Aino Billiet

The present invention relates to an eye-drop composition comprising 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-6H-Purin-6-one, and the use thereof for the diagnosis and treatment of herpetic eye infections in companion animals.

Eye drop composition

This invention provides specifically substituted 1,2,4-thiadiazole derivatives for use in the treatment of an &#x3b1;-synucleopathy such as Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease, Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy and Alzheimer's disease. This invention also provides various methods for producing such substituted 1,2,4-thiadiazole derivatives.

Thiadiazole derivatives for the treatment of neurodegenerative diseases

The invention provides novel 1,2,4-thiadiazole derivatives useful for preventing or treating an &#x3b1;-synucleopathy such as Parkinson's disease, as well as pharmaceutical compositions including them as biologically active ingredients, and methods for manufacturing them. 

Thiadiazole derivatives for the treatment of neuro-degenerative diseases

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Bierbeek, Belgium

Stefaan Wera