Teneoone, Inc.

Teneobio, Inc.

Starlynn Clarke

Wim Van Schooten

Nathan D Trinklein

Shelley Force Aldred

Omid Vafa

Ute Schellenberger

Katherine Harris

Duy Pham

Kevin Dang

Ben Buelow

Anti-PSMA heavy chain antibodies are disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by the expression of PSMA.

Heavy chain antibodies binding to PSMA

Anti-BCMA heavy chain-only antibodies (UniAb) and disclosed, along with methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat B-cell disorders characterized by the expression of BCMA.

Anti-BCMA heavy chain-only antibodies

Multispecific, human heavy chain antibodies (e.g., UniAbs&#x2122;) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.

Multispecific heavy chain antibodies with modified heavy chain constant regions

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Newark, CA, United States of America

Starlynn Clarke