Merck Sharp + Dohme Corp.

Elementis Specialties, Inc.

Stanley Leon Freeman

Harold B Wood

Alan D Adams

Conrad Santini

Jason W Szewczyk

Yong Huang

Eduardus Maria Mangnus

Alart Mulder

Ralph Troy Mosley

Kenneth F Smith

Mark Gregory Matyi, Jr

Nancy Pasquarello Buford

Onno Rienstra

A composition comprising linked segments of: (a) a polyhydroxy segment derived from a compound independently selected an acyclic polyhydric alcohol having 4 to 6 carbon atoms and 4 to 6 reactive hydroxyl groups; a cyclic polyhydric alcohol having 4 to 6 carbon atoms and 4 to 6 reactive hydroxyl groups, a poly(hydroxyethyl) polyethyleneamine having 4 to 6 reactive hydroxyl groups and combinations thereof; (b) polyoxyalkylene segments wherein each hydroxyl group of the polyhydroxyl segment is linked to a polyoxyalkylene segment; (d) and aliphatic end segments or aromatic end segments, each end segment having 6 to 32 carbon atoms and a hydroxyl reactive group, wherein the mole ratio of the polyoxyalkylene segment to the polyhydroxy segment is at least 4:1 and the mole ratio of the aliphatic or aromatic end segment to the polyhydroxy segment is at least 0.25:1.

ICI thickener composition and uses

Methods for preparing hydrophobically modified alkylene oxide urethane branched polymers. In an embodiment, the order of addition of reactants affects the properties of the resultant product urethane. In an embodiment, the time at which one or more reactants are added affects the properties of the resultant product urethane.

Processes for the preparation of rheology modifiers

Bipiperidinyl compounds of the formula: are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.

Bipiperidinyl compounds, compositions, containing such compounds and methods of treatment

Bipiperidyl compounds of the formula: (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119. 

Acyl bipiperidinyl compounds useful as GPR 119 agonists

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Plainsboro, NJ, United States of America

Stanley Leon Freeman