Purdue Research Foundation

Stanley L Hem

Richard F Borch

Joe L White

Harm Hogenesch

Irene A George

Joseph L White

The invention described herein pertains to compounds and conjugates, to compositions, complexes and formulations comprising the compounds and/or conjugates, and to methods of use of the compounds, conjugates and their compositions, complexes and formulations in vaccines and vaccinations and generating immune responses.

Immunogenic compositions and reagents for preparing

Oxy-iron compounds are useful for the treatment and prevention of hyperphosphatemia. Such compounds, particularly those exhibiting high surface area, can be administered orally to bind and inhibit absorption of dietary phosphate, or such compounds can be contacted with the dialysate in a hemodialysis unit to enhance reduction of serum phosphate of patients undergoing hemodialysis.

Method and composition of oxy-iron compounds for treatment of

Dried amorphous aluminum hydroxide gels having substantial acid reacting capability over an extended period of time are prepared by drying the gel after contacting the aqueous liquid gel with an inert organic solvent of sufficient solubility in water to replace water in the gel. The dried gel product and pharmaceutical compositions comprising the gel are also novel.

Process and compositions

Stable dried aluminum hydroxide gels possessing the high acid reactivity of liquid aluminum hydroxide gel are prepared by drying the gel from non-aqueous solvents.

Growing community of inventors

West Lafayette, IN, United States of America

Stanley L Hem