Valco Instruments Company, Inc.

Other

Gabriel Institute, Inc.

Vici Metronics, Inc.

Valeo Instruments Company, L.p.

Valco Instrument Co., Inc

Stanley D Stearns

Huamin Cai

Wayne E Wentworth

H Max Loy, Jr

Chris S Cowles

Ales Plistil

Chris Bishop

Douglas Dailey

Robert Simpson

Dale Ashworth

Donald G Davis

Martin Paul Brisbin

John K McGee

Paul Werner

James A Ramin

David Miller

Santos Anthony Puente

John Michael Kelly

Brian David Russell

Herbert Max Loy, Jr

Matias Hochman

H Max Loy

Systems for use with liquid chromatography for provision of continuous flow or gradient flow in connection with two pumps providing mobile phase to a valve.

System and valve for liquid chromatography

A valve is provided for use with liquid chromatography where liquid is provided to the chromatographic analysis equipment at more than one pressure, including up to ultra-high pressures. High and higher pressure operation are provided by application of force by an internal spring while avoiding wear of components by permitting higher pressure operation by mechanical engagement of an internal element to cause the internal spring to increase the force applied to the rotor, without the addition of external additional loading in the high pressure operation.

Valve for high and ultra-high pressure liquid chromatography

The disclosure pertains to an assembly for use in connecting tubing to a fitting with zero dead volume.

Zero dead volume fitting assembly

A pump for high-pressure and/or nano-scale volumes permits identification of the internal pressure of the pump.

Pump for liquid chromatography with pressure sensor

A tubing and ferrule assembly for use in joining a clad tubing to a fitting. The ferrule is bound to the clad tubing, which includes a partial jacket of stainless steel, such that the inert core protrudes from, and has a common outer diameter with, the jacket. The ferrule is bound to the jacket slightly more distant than necessary for the inert core to contact a fitting. When the ferrule is retained in place, the inert core is compressed and provides a true zero dead volume connection between the clad tubing and the fitting.

A temperature controller for simultaneously controlling the temperatures of a plurality of heating elements for use in chromatographic analysis including columns, detectors, valves, transport lines and other components.

Chromatographic system temperature control system

A dispensing device which disperses medicate through a needle across a zone within a body. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a reservoir in fluid communication with the needle, positioned within the housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with the reservoir-connecting conduit, and a linear drive attached to the needle or to the needle-receiving member. The fluid drive impel fluids from the second reservoir to the reservoir-connecting conduit and thus drives the therapeutic agent from the reservoir during the linear displacement of the needle towards the housing. Fluid communication from the therapeutic agent reservoir to the needle is maintained by the tubing during operation of the linear drive.

Delivery system for injections throughout zone of body

A tubing and ferrule assembly for use in joining a clad tubing to a fitting. The ferrule is bound to the clad tubing, which includes a partial jacket of stainless steel, such that the inert core protrudes from, and has a common outer diameter with, the jacket. The ferrule is bound to the jacket slightly more distant than necessary for the inert core to contact a fining. When the ferrule is retained in place, the inert core is compressed and provides a true zero dead volume connection between the clad tubing and the fitting. The relationship of the ferrule, the clad tubing, and the fitting limits the position of the clad tubing and therefore precludes damaging of the associated valve or component.

A combined pump-injector valve system utilizing a monolithic body to provide the barrel of the pump and as the stator of the valve, thus eliminating any need for connections between a pump and a valve, and therefore the potential for high-pressure leaks or pressure reductions. The combined pump-injector valve permits injection of nanoliter-sized samples into a chromatographic column, which is sealed during loading of the sample and filling of the pump, such that complete analyses can be completed with microliters of mobile phase with nanoliters of a sample. The pump-injector valve system further includes a pressure sensor external the barrel of the pump and may include an interim position intermediate loading and injection where the contents of the barrel may be pressurized to a desired pressure.

Pump and injector for liquid chromatography

A combined pump-injector valve utilizing a single piece as the barrel of the pump and as the stator of the valve, thus eliminating any need for connections between a pump and a valve, and therefore the potential for high-pressure leaks or pressure reductions. The combined pump-injector valve permits injection of nanoliter-sized samples into a chromatographic column, which is sealed during loading of the sample and filling of the pump, such that complete analyses can be completed with microliters of mobile phase with nanoliters of a sample.

Growing community of inventors

Houston, TX, United States of America

Stanley D Stearns