Exxonmobil Research and Engineering Company

Stanley Bower

You Chen

Thomas E Wall

Robert Christopher Brown

Nicholas Bauman

Jennifer Coppersmith

Srividya Akella

Wendy Loza

Vincent A Bielinski

Kate Lyons Boyd

Paul G Roessler

The invention provides a method of culturing a microorganism that produces a free fatty acid in a culture medium, comprising culturing the microorganism in the culture medium comprising a sufficient amount (e.g., at least about 0.5 mM) of a carboxylate counterion source to enhance viability of the microorganism in the culture medium. Fatty acids produced using the methods of the invention can be used to synthesize a variety of products, including biofuels.

Culturing a microorganism in a medium with an elevated level of a carboxylate counterion source

The invention provides transgenic photosynthetic microorganisms that include non-native genes encoding polypeptides having lipolytic activity for production of free fatty acids and fatty acid derivatives, and methods of producing free fatty acids and fatty acid derivatives using the transgenic microorganisms disclosed herein. The invention also provides transgenic microorganisms that include non-native genes encoding polypeptides having lipolytic activity, and novel genes encoding polypeptides demonstrating lipolytic activity.

Production of fatty acids and fatty acid derivatives by recombinant microorganisms expressing polypeptides having lipolytic activity

The present invention relates to the regulation of a toxin and/or antitoxin genes in a genetically engineered microorganism, such as cyanobacterial or eukaryotic algal strains, in particular for preventing unintentional and/or uncontrolled spread of the microorganisms. The present invention also includes methods of controlling the growth and/or survival of the engineered microorganism

Regulation of toxin and antitoxin genes for biological containment

Growing community of inventors

San Diego, CA, United States of America

Stanley Bower