Linnet Biopharmaceuticals, Inc.

Stan W Linnet

William K Chan

Liang Xue

Timothy N Linnet

The teachings provided herein generally relate to compositions comprising rutaecarpine derivatives that activates CYP1A2 through enzyme induction. The uses for such a derivative can include removing caffeine from a subject, improving sleep, treating insomnia, treating caffeine toxicity, treating caffeine addiction and withdrawal symptoms, and the like. Caffeine is just one example of a substrate that can be removed using the derivatives taught herein, and other examples, including theophylline, are provided herein.

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Redding, CA, United States of America

Stan W Linnet