Edwards Lifesciences Cardiaq LLC

Medtronic Cv Luxembourg S.a.r.l.

Medtronic Corevalve LLC

Stan Komatsu

Hung Nguyen

Than Nguyen

J Brent Ratz

Arshad Quadri

Jacques Seguin

Georg Börtlein

Georg Boertlein

Robrecht Michiels

Jacques R Seguin

MyKim Nguyen

Yen Liao

Jacques Séguin

Kalathi Thygarajan

Brent J Ratz

Mykim Nguyen

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. The valve body has an upstream end and a downstream end, and a diameter at the downstream end is greater than a diameter at the upstream end.

Replacement heart valve

Methods for delivering a prosthetic heart valve include advancing a delivery catheter containing the prosthetic heart valve to a deployment native heart valve, advancing an inner core movably coupled to a restraining sheath of the delivery catheter to expose a first end of the prosthetic heart valve, and advancing the inner core and the restraining to expose a second end of the prosthetic heart valve. The delivery catheter can include a distal flange located at a distal end of an outer core of the catheter body, configured to restrict distal longitudinal displacement of the prosthetic heart valve, and a retaining structure located proximally from the distal flange along the outer core of the catheter body, configured to restrict proximal longitudinal displacement of the prosthetic heart valve.

Methods for delivering a self-expanding valve

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. The valve may be delivered transluminally or transmyocardially using a thorascopic or other limited access approach using a delivery catheter. Preferably, the initial partial expansion of the valve is performed against the native valve annulus to provide adequate anchoring and positioning of the valve as the remaining portions of the valve expand. The valve may be delivered using a retrograde or antegrade approach. When delivered using a retrograde approach, a delivery catheter with a pull-back sheath may be used, while antegrade delivery is preferably performed with a delivery catheter with a push-forward sheath that releases the proximal end of the valve first.

System and method for transapical delivery of an annulus anchored self-expanding valve

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Laguna Hills, CA, United States of America

Stan Komatsu