University of Virginia Patent Foundation

The University of Birmingham

Stacy Alyse Malaker

Donald F Hunt

Mark Cobbold

Victor H Engelhard

Jeffrey Shabanowitz

Kara L Cummings

Rebecca C Obeng

Angela Lee Zarling

Angela L Ambakhutwala

A set of target peptides are presented by HLA A*0101, A*0201, A*0301, B*4402, B*2705, B*1402, and B*0702 on the surface of disease cells. They are envisioned to among other things (a) stimulate an immune response to the proliferative disease, e.g., cancer, (b) to function as immunotherapeutics in adoptive T cell therapy or as a vaccine, (c) facilitate antibody recognition of tumor boundaries in surgical pathology samples, (d) act as biomarkers for early detection and/or diagnosis of the disease, and (e) act as targets in the generation antibody-like molecules which recognize the target-peptide/MHC complex.

Target peptides for immunotherapy and diagnostics

Growing community of inventors

Menlo Park, CA, United States of America

Stacy Alyse Malaker