Corning Incorporated

Srikanth Raghavan

John Christopher Mauro

Ye Fang

Joydeep Lahiri

Brian L Webb

Yulong Hong

Valerie Claudine Lacarriere

Fang Lai

Alexander Mikhailovich Efremov

Valerio Pruneri

Sergey Yurevich Ten

Salvatore Morasca

Alain R E Carre

Alain Re Carre

The invention relates to G protein-coupled receptor (GPCR) microarrays on porous substrates for structural or functional analyses of GPCRs, and methods of preparing porous substrate surfaces for receiving membranes that comprise GPCRs. In one embodiment, a GPCR microarray of the invention comprises a membrane adhered to an upper surface of a porous substrate, the membrane spanning across a plurality of pores on the porous substrate to form a plurality of cavities having sufficient geometry to permit entry of assay reagents into each cavity, thereby allowing access of assay reagents to both sides of GPCR in the membrane.

Membrane arrays and methods of manufacture

An optical fiber system comprising: (i) a dispersion pre-compensator including dispersion compensating fiber DCF characterized by the overall dispersion value Dat the operating wavelength &#x3bb;; and (ii) a passive optical network (PON) including a plurality of transmission paths provided by a plurality of optical fibers, said plurality of transmission paths having a minimum and maximum dispersion value Dand D; wherein the dispersion pre-compensator includes an output port operatively coupled to an input port of the a passive optical network and &#x2212;D&#x3c;D&#x3c;&#x2212;D.

Optical fiber with low second order distortion

A conversion method for converting a unipolar voltage data stream into a carrier-suppressed return-to-zero (CSRZ) optical data stream includes modulating a continuous optical wave with an encoded nonreturn-to-zero (NRZ) voltage data stream for providing a CSRZ optical data stream of full-width at half-maximum (FWHM) pulse width less than one-half of the transition time of the encoded nonreturn-to-zero (NRZ) voltage data stream between logical states for a reduced pulse width. The modulating circuit is either a duobinary modulator driven with a swing of &#xb1;2Vor an optical time domain multiplexed plurality of nonreturn-to-zero (NRZ) modulators with phase shifting and differential encoding.

Unipolar electrical to CSRZ optical converter

A device ( ) in a system ( ) modulates an optical signal ( ) and tunes the duty cycle of the optical signal ( ) for optimizing system performance as a response of the duty cycle. The device ( ) includes a tunable duty-cycle Mach-Zehnder interferometer (MZI) acting as a pulse-width shaper ( ) for modulating the optical signal ( ) and tuning the duty cycle of the optical signal ( ). The MZI ( ) has a transmittance transfer function of the interferometer ( ). At least one electrode structure ( ) generates a DC voltage and an AC voltage for biasing and controlling the swing of the Mach-Zehnder interferometer ( ) with the respective amplitudes of the DC and AC voltages such that the maximum power transmittance point on the transfer function is less than 100% for tuning the duty cycle of the optical signal ( ) such that system performance is optimized.

Variable duty cycle optical pulses

Growing community of inventors

Ithaca, NY, United States of America

Srikanth Raghavan