Becton Dickinson and Company Limited

Biomerieux, Inc.

Spencer Lovette

Mark A Talmer

Dwight Livingston

Robert L Campbell

Thomas D Haubert

Tong Zhou

Timothy Roy Hansen

Kevin Bailey

Andre Scherz

Jack H Kessler

Ammon David Lentz

James A Prescott

Scott D Collins

Michael L Marshall

Gregory S Kramer

Christopher M Embres

Michael Justin Lizzi

Scott Nicholas Danhof

Melody M H Kuroda

M Scott Ulrich

Donald E Gorelick

Gerard J Sevigny

Jared Ian Bullock

Artis R Lockhart

Kristin Weidemaier

Adam C Curry

James Arthur VanGordon

Andrea Liebmann-Vinson

Eric Fallows

David S Sebba

Randy J Somerville

Kevin G Dolan

Ernie Ritchey

Ian MacGregor

Miroslaw Bartkowiak

Wendy Dale Woodley

Erin Gooch Carruthers

Jeffrey S Ojala

Andrew J Violette

Jo-ann Loh

Eric A Fallows

Melody MH Kuroda

Methods for an instrument including a light source of are provided. A method for an instrument including a light source includes providing light from the light source to a target location in a process chamber. The method includes receiving the light at a sensor. The method includes determining, using data from the sensor, a first position of the light at the target location. Moreover, the method includes determining whether to adjust the light to a second position at the target location. Related instruments are also provided.

Methods for aligning a light source of an instrument, and related instruments

Provided herein are methods, systems, and devices for detecting and/or identifying one or more specific microorganisms in a culture sample. Indicator particles, such as surface enhanced Raman spectroscopy (SERS)-active nanoparticles, each having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest, can form a complex with specific microorganisms in the culture sample. Further, agitating magnetic capture particles also having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest can be used to capture the microorganism-indicator particle complex and concentrate the complex in a localized area of an assay vessel for subsequent detection and identification. The complex can be dispersed, pelleted, and redispersed so that the culture sample can be retested a number of times during incubation so as to allow for real-time monitoring of the culture sample.

Methods, systems, and devices for detecting and identifying microorganisms in microbiological culture samples

A system for automatically processing a biological specimen is provided that includes an elevator comprising a plurality of shelves configured to receive a plurality of sample trays. The trays may comprise a plurality of sample containers containing a sample and having a plurality of respective caps engaged therewith. The trays may further include a plurality of centrifuge tube racks each containing a plurality of centrifuge tubes. The system may include a first transport mechanism, a second transport mechanism and a third transport mechanism. The system may include a chain-of-custody device configured to read identifiers on each of the containers. The system may also include a pipetting device configured to remove a portion from the sample containers and dispense the sample into the centrifuge tubes.

System and method for automated sample preparation

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Mount Vernon, NH, United States of America

Spencer Lovette