Siemens Healthcare Diagnostics Gmbh

Spencer Lin

Ryan Spears

Christopher Reamer

Michael J Pugia

Karlheinz Hildenbrand

Lloyd S Schulman

Robert J Owens

Seema Sinha

Kwasi Osae-Kwapong

Omar Quraishi

Michele Smith

SunRay DiFrancesco

Dharini Rawal

Debra Hovanec-Burns

Processes for quantifying an amount of functional groups immobilized on a solid support are described herein. The processes allow for determining whether sufficient functional groups are provided on a solid support for the attachment of a first binding pair member for the detection of a target analyte.

Quantitation of functional groups on solid supports

A human insulin-like growth factor (IGF) binding protein stock solution and method of making the same include a non-recombinant human IGF binding protein-3 (nr-IGFBP-3) in an aqueous buffered medium. The concentration of the nr-IGFBP-3 in the stock solution ranges from about 16 micrograms per milliliter (μg/ml) to about 40 μg/ml. A kit includes a set of calibrators for nr-IGFBP-3. The set of calibrators includes the nr-IGFBP-3 in different concentrations.

Non-recombinant human insulin-like growth factor binding protein concentrate

A device for detecting an analyte in a fluid sample includes a liquid permeable composition for making a physical separation between compositions of the sample or for reacting with components. The liquid permeable composition has adhesive properties and can be used to make a multi-layered test strip or the composition can be used in the sample wells of microfluidic devices.

Liquid permeable composition in dry reagent devices

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Spencer Lin