Showa Denko Kabushiki Kaisha

Other

Masayuki Ishikawa

Kawasumi Kagaku Kougiyou Kabushiki Kaisha

Soyao Moriguchi

Hiroshi Suzuki

Chozo Inoue

Yukuo Eguchi

Hisashi Ebisawa

Tamami Koyama

Akiko Sugimoto

Isao Kaiho

Michio Abe

Yasuo Iwata

Yoshito Nakayama

Fujinori Sasaki

Motoaki Satoh

Tae Ishii

Katsuhiko Gotoh

Yoshiko Kurima

Seiji Shioda

Hiroko Watanabe

Enzyme activity is measured promptly with a high accuracy by introducing an enzyme, the activity of which is to be measured, into a column comprising a hollow tube packed with a filler comprising a support and a substrate that can be recognized by the enzyme, which is immobilized on the support, and measuring the amount of the obtained decomposition product of the substrate.

Method of measuring enzyme activity by using a column having an

The active support substance and the adsorbent for chromatography, which have got all of the properties desired for affinity chromatography, can be constituted by a porous copolymer comprising gel copolymer which is principally composed of (A) a glycidyl monovinylester or glycidyl monovinylether and (B) alkyleneglycol divinylester, and combination groups to be bound to ligands through a covalent bond, the (A) component being crosslinked by the (B) component, and the combination groups being bound to epoxy groups of the (A) component.

Active support substance and adsorbent for chromatography

Disclosed is an adsorbent composed of porous beads of uncrosslinked or crosslinked chitosan, wherein protein A or lectin is covalent-bonded trough a bonding group to the amino group of glucosamine constituting the chitosan in the case of uncrosslinked chitosan or to the amino group of glucosamine constituting the chitosan and an amino group of a crosslinking agent in the case of crosslinked chitosan. The adsorbent composed of the chitosan porous beads to which protein A is bonded through a bonding group is used for absorption removal of interleukin 2 inhibitor. The adsorbent composed of the chitosan porous beads to which lectin is bonded through a combination group is used as an adsorbent for affinity chromatography. An adsorbent composed of porous beads of uncrosslinked or crosslinked chitosan is used for adsorbing immunoglobulin. An adsorbent composed of uncrosslinked or crosslinked chitosan wherein an .omega.-carboxylalkanoyl group and an acyl group have been introduced is used as a carrier for chromatography.

Adsorbent composed of porous beads of chitosan and adsorption method

A process for the optical resolution of DL-cysteine which comprises

Optical resolution process for DL-cysteine

The 4(3H)-quinazolinone compounds of the formula (I) ##STR1## wherein R.sub.1 and R.sub.3, independently from each other, represent a lower alkyl group;

4(3H)-Quinazolinone derivatives, process for production thereof, and

A 5,6,7-substituted-2,4(1H,3H)-quinazolinedione compound of the formula (I), ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, A and B are as defined in claim 1 and its acid addition salt; and a vasodilating and hypotensive composition containing the aforesaid compound.

Quinazolinde-dione compounds, process for production thereof and

A novel production process of .beta.-chloroalanine from chloroacetaldehyde is provided. In this process, a bisulfite or sulfite addition compound of chloroacetaldehyde is first reacted, in an aqueous solution, with ammonia and, then, reacted with hydrocyanic acid or a salt thereof. Thus, .alpha.-amino-.beta.-chloropropionitrile is formed. This .alpha.-amino-.beta.-chloropropionitrile is hydrolyzed under an acidic condition to form .beta.-chloroalanine.

Process for production of .beta.-chloroalanine

Growing community of inventors

Yokohama, Japan

Soyao Moriguchi