Johns Hopkins University

Other

Boston Scientific Scimed, Inc.

The University of Akron

Jhpiego Corporation

Drizzle Health LLC

Soumyadipta Acharya

Sung Jin Sunwoo

Qian Liu

Kimberly Ashman

Margaret Glancey

Abimbola Aina-Mumuney

Deepika Sagaram

Karin Hwang

Karin J Blakemore

Shishira Nagesh

Andrew D Bicek

Elizabeth Anne Stokley

Umang Anand

David A Kass

Clifford R Weiss

Youseph Yazdi

Chao-Wei Hwang

Kevin Colbert

Dale H Mugler

Nichaluk Leartprapun

Viachaslau Barodka

Peter V Johnston

Myron L Weisfeldt

Christopher Chiang

Timothy P Harrigan

Patience Osei

Matthew Petney

Michael Parlato

Madeleine Clegg

Girish Singhal

Laura Elizabeth Schiffrin Scavo

Adam C Goodwin

William A Patterson

Mary Katherine O'Grady

Siavash Parkhideh

Thora Thorgilsdottir

Christopher Brandon Courville

Vaishakhi Mayya

Chandrakant Ruparelia

Sean Mongale

Mary O'Grady

Nahyun Kate Cho

Peter Truskey

James Waring, Iii

William Chen

Joshua Budman

Paul Fearis

Harshard Sanghvi

Maxim Budyansky

Brian Ma

Matthew Means

Courtney C Haswell

Hargun S Khanna

Reeve Ilse Heinis

Yun Long

Nimra Taqi

Erin Reisfeld

Raghavan Gopalakrishnan

Anandi Mahadevan

Judy C Doong

Nicholas Radant

Timothy Campbell

Justin Chang

William Alexander LeMay Patterson

Thomas Reifsnyder

Ashley Polhemus

Brandon Doan

Jill Andrews

Yi Rose Huang

Ezra Taylor

HarshadKumar Sanghvi

Thembi Mdluli

Aaron Enten

Sherri Hall

Brandon Craft

Britni Crocker

Elaine Yang

Sami Messai

Neil Rens

Jessica Jeang

Meagan Hawes

Phillip J Oh

Vanessa C Pau

Jason Onslow Leroy Johnson

Lu Zhao

Tristan Ford

Arjun Shailesh Vachhani

Noah Lampel Greenbaum

Jackline Wanjala

Willibrord Shasha

Majd Alghatrif

Bailey Topper

Guilherme Barros

B Westbrook Bernier

Trent Langston

Christopher B Courville

George Major Chen

Rose Yi Huang

Yuan-Ping Li

Sherri Jane Hall

A device for selectively capturing mycobacteria comprises a substrate and a capture polymer layer of poly-diallyldimethyl ammonium chloride, wherein the capture polymer layer is covalently linked onto the substrate via a UV-initiated polymerization reaction of a solution comprising diallyldimethyl ammonium chloride and a photoinitiator in water purged of dissolved oxygen, and wherein the UV exposure time is 30 seconds to 4 minutes at a power density of about 20 to about 25 mW/cm. A kit can comprise the device. A microfluidic chip comprises at least a portion of at least one channel sidewall coated with a capture polymer layer of poly-diallyldimethyl ammonium chloride. A method for manufacturing the device includes plasma treating a substrate, providing a solution comprising diallyldimethyl ammonium chloride and a photoinitiator in water purged of dissolved oxygen, and coating the plasma-treated substrate via a UV-initiated polymerization reaction.

Apparatus and methods for selective capture of mycobacteria

An insect trap analysis system may detect an insect specimen on a trap mechanism of an insect trap. The insect trap analysis system may control, based on detecting the insect specimen on the trap mechanism, one or more mechanical devices to: adjust a position of the insect specimen relative to a position of an image capture device associated with the insect trap, or adjust the position of the image capture device relative to the position of the insect specimen. The insect trap analysis system may cause, while controlling the one or more mechanical devices to adjust the position of the image capture device or the position of the insect specimen, the image capture device to capture a plurality of images of the insect specimen from a plurality of different angles relative to the insect specimen, and may perform an action associated with the plurality of images.

Insect specimen analysis system

A mosquito surveillance device includes one or more mosquito traps having a camera capable of taking images of mosquitos and transmitting the images electronically to a receiver. Suitable traps include an ovitrap, for example. Images may be transmitted from inside or outside the trap to a receiver using low bandwidth cellular phone networks. The images are processed and displayed using software forming mosquito data. The images may be analyzed and the number of live mosquitos identified, the number of dead mosquitos identified, the species of mosquitos identified, or mapped vector densities in real time identified preferably at high resolution.

System for insect surveillance and tracking

The present invention is directed to a bio-fluid detector such as a hemoglobin detector having the capability of receiving, storing and transmitting health information utilizing a portable transmitter and receiver including electronic PDAs such as cell phones. Further, the present invention utilizes a non-invasive hemoglobin detector that is connected to a portable transmitter-receiver such as PDAs including, but not limited to, cell phones.

Non-invasive bio-fluid detector and portable sensor-transmitter-receiver system

The present application relates to systems and methods for non-invasively determining at least one of left ventricular end diastolic pressure (LVEDP) or pulmonary capillary wedge pressure (PCWP) in a subject's heart, comprising: receiving, by a computer, a plurality of signals from a plurality of non-invasive sensors that measure a plurality of physiological effects that are correlated with functioning of said subject's heart, said plurality of physiological effects including at least one signal correlated with left ventricular blood pressure and at least one signal correlated with timing of heartbeat cycles of said subject's heart; training a machine learning model on said computer using said plurality of signals for periods of time in which said plurality of signals were being generated during a heart failure event of said subject's heart; determining said LVEDP or PCWP using said machine learning model at a time subsequent to said training and subsequent to said heart failure event.

Device and method for non-invasive left ventricular end diastolic pressure (LVEDP) measurement

The present invention relates to bodysuits for use as personal protective equipment comprising a torso portion comprising a front side; a back side including a sealable port through which a wearer can enter and exit the bodysuit when donning or doffing the bodysuit, respectively; a waist region; a neck opening; a pair of upper limb openings; and a pair of lower limb openings; two arm portions each extending from one of the upper limb opening; and two leg portions each extending from one of the lower limb opening and methods for the removal of such body suits.

Suit designs and doffing methodologies for personal protective equipment to prevent the spread of infectious agents to healthcare workers

A system, method and apparatus for monitoring uterine and/or cervical activity indicative of labor in a patient. The system includes a medical device and a data processor in communication with the medical device. The medical device includes a structural component, a first electrode attached to the structural component, and a second electrode attached to the structural component. The structural component is structured to be in contact with a cervical surface and a vaginal surface of the patient, such that said first electrode is in electrical contact with said cervical surface and said second electrode is in electrical contact with said vaginal surface. The first electrode is adapted to receive an electrical activity of the cervical surface and the second electrode is adapted to receive an electrical activity of the uterus through the vaginal surface. The data processor is adapted to process the electrical activity of the electrodes to detect contractions on a surface of the patient indicative of labor.

Preterm labor monitor

An embodiment in accordance with the present invention provides a valve including a housing having a top portion and a bottom portion. The top portion of the housing defines a first and second nozzle, and the bottom portion of the housing defines an opening. A diaphragm has an open position and a closed position, and the diaphragm is disposed between the top portion of the housing and the bottom portion of the housing. A first fluid flow path between the first nozzle and the second nozzle is defined by the housing and the diaphragm, when the diaphragm is in the closed position. A second fluid flow path between the opening and the first nozzle is defined by the housing and the diaphragm, when the diaphragm is in the open position. Such a valve can be used for a number of purposes including hemodialysis procedures.

Implantable three-way diaphragm valve

A point-of-care, screening kit for use by a heath care worker to create custom test strips for screening the bodily fluids of an individual for various, medical conditions includes: (a) a plurality of reagents (), (b) a substrate () configured to: i) receive one of the reagents and react with it so as to cause it to acquire a first characteristic color, and, ii) upon the addition of the individual's bodily fluid to the substrate, acquire, as a result of the formulation of each of the reagents, a second, dichotomous characteristic color when the individual has a specific one of the various, medical conditions. This kit also includes: (c) a plurality of containers () having indicia () that are reflective of the reagent within the container and which of the various medical conditions is being screened for with the use of the container and the characteristic first and second colors which are indicative of the individual having a screened for medical condition, and (d) one of the reagents being a protein reagent that includes appropriate quantities of: water, isopropyl alcohol, citric acid monohydrate, sodium citrate iribasic monohydrate, tetrabromophenol blue and tartrazine.

Point-of care, medical condition screening kit

Featured is an apparatus an apparatus including a monitoring and sensing means, an electrode patch and a control device operably coupled to each of the sensing means and the electrodes and outputs signals to the electrodes for purposes of stimulating the phrenic nerve to thereby cause breathing by natural contraction of the diaphragm. The control device is configured and arranged to initially localize the phrenic nerve with respect to a given set of electrodes that is effective, when appropriately energized, for stimulating the phrenic nerve to establish negative pressure induced respiration in the body, based on the output signal(s) from the monitoring and sensing means. After such initially localizing; the control device thereafter repetitively outputs stimulation signals via the given set of electrodes so as to thereby continuously stimulate negative pressure induced respiration. Also featured are methods related thereto.

Portable negative pressure ventilation device and methods and software related thereto

General diagnostic and real-time application of digital Hermite functions allows features to be extracted from a measured signal through expansion of the measured signal. Specifically, the digital Hermite functions represent the shape of the measured signal in a set of vectors derived from a symmetrical tridiagonal matrix. This allows for efficient computation of the Hermite expansion coefficients, in real-time, to represent the expanded signal. The signal expansion also allows any artifacts, such as noise, to be isolated and removed, allowing the underlying signal of interest to be revealed.

General diagnostic and real-time applications of discrete hermite functions to digital data

Growing community of inventors

Baltimore, MD, United States of America

Soumyadipta Acharya