Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts

Eberhard-karls-universitaet Tuebingen Universitaetsklinikum

Eberhard Karls Universität Tuebingen Medizinische Fakultaet

Eberhard-karls-universität Tübingen Universitätsklinikum

Sorin Armeanu-Ebinger

Sascha Bossow

Wolfgang J Neubert

Michael Bitzer

Ulrich Manfred Lauer

Martina Zimmermann

Harald Surowy

Jens Gesche

Guido Seitz

Wolfgang Neubert

The present invention relates to a nucleic acid molecule which encodes a splice variant of the human P2RX7 receptor, and nucleic acid molecules derived therefrom, a recombinant vector containing said nucleic acid molecules, a host containing said recombinant vector, a polypeptide encoded by said nucleic acid molecules, a host cell expressing said polypeptide, a binding molecule binding to said polypeptide, a pharmaceutical composition comprising said binding molecule, a method for the production of the isolated polypeptide, and other methods and uses in connection therewith.

Tumor marker for the rhabdomyosarcoma

The present invention relates to a genetically modified Paramyxovirus, a pharmaceutical composition comprising this paramyxovirus, the use of a genetically modified Paramyxovirus for the therapeutic and/or prophylactic treatment of a tumor disease, and a method for the production of a pharmaceutical composition for the therapeutic or prophylactic treatment of a tumor disease.

Genetically modified paramyxovirus for treatment of tumor diseases

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Tuebingen, Germany

Sorin Armeanu-Ebinger