Delphi Genetics S.a.

Immunehealth

Sophie Scohy

Jean-Christophe Renauld

Philippe Gabant

Cédric Szpirer

Alain Vanderplasschen

Muriel Lemaire

Laurent Gillet

Laurie Dumoutier

Yannick Nizet

Thierry Van Reeth

Methods are disclosed for generating antibodies and an expression vector used to express protein(s) which provoke the antibody response. The expression vector may be useful in generating an antibody directed to an antigen, comprising a gene in operable linkage with a promoter, which gene encodes upon expressing a fusion protein comprising (i) CD134L, a fragment, homologous or orthologues protein thereof as N-terminal moiety of the fusion protein; and (ii) all or part of an antigenic protein as C-terminal moiety of the fusion protein. To generate the antibodies, the vector is injected into a subject animal, which produces a fusion protein, against which antibodies are generated.

Method for producing antibody using 'naked' expression vector expressing type II transmembrane fusion protein

The present invention is related to a method for a high through-put screening detection of genetic modifications in genome engineering and a system for homologous recombination of an exogenous nucleotide sequence into a target cell genome sequence.

Method for a (high through-put) screening detection of genetic modifications in genome engineering

Growing community of inventors

Nivelles, Belgium

Sophie Scohy