Biomet Deutschland Gmbh

Technische Universitä{umlaut Over ( )}T Dresden

Technische Universitát Dresden

Sophie Roessler

Hartmut Worch

Dieter Scharnweber

Thomas Hanke

Michel Dard

René Beutner

Bernd Schwenzer

Jan Michael

Andreas Sewing

A metallic object has a coating made of a thin metal oxide layer and nucleic acids or nucleic acid derivatives bonded thereto. The nucleic acid compounds have 5'-terminal or 3&#x2032;-terminal molecule areas that are incorporated stably into the metal oxide layer. The unincorporated areas of the nucleic acid compounds that are not incorporated into the metal oxide layer are freely accessible for subsequent interactions with other molecules such as complementary nucleic acids having active ingredients attached thereto.

Metallic object with a nucleic acid coating and derivatives thereof and method for producing said object

A biomimetically produced bone-analogous coating, comprising organic and inorganic main constituents, is suitable for coating metallic implant materials of any desired surfaces. The coating comprises a collagen matrix mineralized with calcium phosphate.

Process for the coating for metallic implant materials

Growing community of inventors

Dresden, Germany

Sophie Roessler