University of Washington

Soon Joon Yoon

Matthew N O'Donnell

Ivan Pelivanov

Ruikang K Wang

Tueng T Shen

Jinjun Xia

Shaozhen Song

Chen-Wei Wei

Elena Petrova

Thu-Mai Nguyen

Lukasz Ambrozinski

David Li

Liang Gao

Methods and systems for measuring one or more properties of a soft material employ air transmitted ultrasound that is reflected from the soft material to generate a mechanical wave in the soft material. A method of measuring one or more properties of a soft material includes transmitting ultrasound through air to an interface boundary between the soft material and air. Force is applied to the soft material by reflecting the ultrasound from the soft material. A mechanical wave is generated in the soft material as a result of the force applied to the soft material. Propagation of the mechanical wave in the soft material is measured with an imaging system. One or more properties of the soft material is determined based on the measured propagation of the mechanical wave in the soft material.

Non-contact acoustic radiation force based (ARF-based) generation of broad bandwidth mechanical waves using air-coupled ultrasound

A non-contact photoacoustic spectrophotometry system is configured to measure an absorption spectrum of a material. The system includes a modulated light source such as tunable pulsed laser that generates laser pulses to produce photoacoustic signals in the material. A non-contact detector monitors the surface of the container for the material. The detector includes a second light source, such as a continuous wave laser, focused on the surface of the container, and transmits reflected light to an interferometer, for example, a Sagnac interferometer. The interferometer produces an interference signal from the received light that is proportional to the acoustic pressure, which is transmitted to a computer to calculate an absorption coefficient. Using a plurality of wavelengths from the tunable pulsed laser, an absorption spectrum may be generated.

Non-contact photoacoustic spectrophotometry insensitive to light scattering

Methods and system for producing combined photoacoustic/ultrasonic image frames use a low-power narrow beam laser to direct sequential pulses along a path overlying an internal region of interest. Photoacoustic responses are received and used to generate sub-frames. Between each of the laser pulses a plurality of ultrasound pulse-echo beams are sequentially emitted towards the region of interest, and the reflections are received and used to generate ultrasound sub-frames. The photoacoustic sub-frames are combined to produce a photoacoustic frame, and the ultrasound sub-frames are combined to produce an ultrasound frame. The photoacoustic and ultrasound frames are combined to produce an image frame. The method and system are suitable for producing real-time, high-contrast video.

Real-time photoacoustic and ultrasound imaging system and method

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Seattle, WA, United States of America

Soon Joon Yoon