Bristol-myers Squibb Compnay

Soo S Koo

Jagabandhu Das

Scott Hunter Watterson

Anurag S Srivastava

Robert V Moquin

Disclosed are compounds of Formula (I): (I) or stereoisomers, salts, or prodrugs thereof, wherein: (i) R1 and R2 are independently C-Calkyl, or (ii) Rand Rtogether with the carbon atom to which they are attached, form a cyclic group; and Q is H, Calkyl, phenyl or 5- to 6-membered heteroaryl substituted with zero to 3 substituents, and G is defined herein. Also disclosed are method of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. There compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and chronic inflammatory disease. 

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Hockessin, DE, United States of America

Soo S Koo