Daewoong Pharmaceutical Co., Ltd.

Medipost Co., Ltd

Daewoong Bio Inc.

Ewha University-Industry Collaboration Foundation

Soo Jin Choi

Young Soo Kim

Wonil Oh

Byung Goo Lee

Yong Kim

Yoon-Sun Yang

Jong Wook Chang

Hee Kyoon Yoon

Seong Soo Oh

Ju-Yeon Kim

Hye Jin Kim

Seung Jae Lee

Yong Suk Jin

In Woo Kim

Ji Duck Kim

Sung Woo Park

Sung Jae Lee

Seong Cheol Moon

Sun Ah Jun

Joon Hwan Lee

Hong Bae Jeon

Hong Chul Yoon

Kwang Joo Kim

Jeong Hyun Son

Jin Ho Choy

Hoon Lim

Ie Rang Jeon

Yun Sun Yang

Jihye Kwak

Dong Hyon Kim

Wol Young Kim

Yoon Seok Song

Yeon Jung Yoon

Yoon Sun Yang

Jae Min Oh

Young Mook Lim

Jang Young Lee

Tae Yi Kim

A pharmaceutical composition comprising HLA-A2-expressing mesenchymal stem cells as an effective ingredient and its use in prevention or treatment of inflammatory disease are disclosed. The mesenchymal stem cells expressing HLA-A2 on the surface thereof inhibit the secretion of the inflammatory cytokine TNF-a and increase the expression of the anti-inflammatory markers CD163 and Arg-1, so that the pharmaceutical composition comprising the mesenchymal stem cells as an effective ingredient can be advantageously used for suppressing inflammation or treating inflammatory diseases.

Pharmaceutical composition comprising mesenchymal stem cells as effective ingredient for prevention or treatment of inflammatory disease

A use of a composition comprising umbilical cord blood-derived mesenchymal stem cells for inducing differentiation and proliferation of neural precursor cells or neural stem cells to neural cells is provided, the composition being effective for the treatment of nerve injury diseases.

Administering umbilical cord blood-derived mesenchymal stem cells to treat nerve injury

Neural cell proliferation induced through the culture of neural cells with umbilical cord blood-derived mesenchymal stem cells

The present invention relates to an improved method for synthesizing meropenem trihydrate[(1R,5S,6S)-2-[((2'S,4&#x2032;S)-2&#x2032;-dimethylaminocarbozyl)pyrrolidin-4&#x2032;-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid, trihydrate], which is a novel carbapenem antibiotic.

Method for preparing meropenem using zinc powder

The present invention relates to novel Forms A, B, C, D, E, F and G of crystalline 9-[2-[phosphonomethoxy]ethyl]adenine bis-pivaloyloxymethyl ester, i.e., adefovir dipivoxil, and processes for preparing them. According to the present invention, said novel crystal forms having a high purity can be obtained by a simple method and in a high yield.

Crystal forms of adefovir dipivoxil and processes for preparing the same

This invention relates to a method of preparing a benzoimidazole derivative at high purity and high yield so as to enable the production of the benzoimidazole derivative compound as an antagonist against a vanilloid reactor-1, and particularly to a method of preparing a benzoimidazole derivative at high purity and high yield, wherein the benzoimidazole derivative is synthesized using a novel intermediate, namely, benzaldehyde, and thereby the preparation process is simple so that it can be applied to production.

Method of preparing benzoimidazole derivatives

The present invention relates to a process for preparation of aripiprazole crystal form II by recrystallizing aripiprazole in a mixture of acetone and 1-methoxy-2-propanol or a single solvent of 1-methoxy-2-propanol. The simple process according to the present invention can produce aripiprazole crystal form II with high purity and high yield in a mass scale.

Process for the preparation of anhydrous aripiprazole crystal form II

Provided are a boron compound-layered double hydroxide (LDH) nanohybrid in which a boron compound for boron neutron capture therapy is intercalated in between layers of LDH, a method of preparing the boron compound-LDH nanohybrid, and a pharmaceutical composition including the boron compound-LDH nanohybrid, which can be used in boron neutron capture therapy.

Boron compound-layered double hydroxide nanohybrid, method of preparing the boron compound-LDH nanohybrid, and pharmaceutical composition comprising the boron compound-LDH nanohybrid

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Yongin, South Korea

Soo Jin Choi