Other

Mogam Biotechnology Research Institute

Neurotech Pharmaceuticals Co., Ltd.

Soo-Il Chung

Doo-Hong Park

Jae-Seung Yoon

Byoung S Kwon

Byung Soo Youn

Seung Jae Baek

Ju-Hyung Ahn

Yeup Yoon

Jung-Seob Kim

Jong-Mook Kim

Eun-Kyoung Lee

Sun-Mo Oh

Kong-Ju Lee

Kwang-Hee Baek

The present invention relates to an expression vector for animal cells. Specifically, the present invention relates to an expression vector, pMS vector, pSG vector and pMSG vector, including the human &#x3b2;-globin 5' MAR complementary sequence or/and the transcription termination site of the gastrin gene. An expression system using an expression vector of the present invention can successfully produce recombinant proteins in various animals cells and recombinant protein having a unique structure and function.

Expression vector for animal cell

The present invention relates to a variant of Lkn-1(shLkn-1) with enhanced biological activity, which is a truncated form of Lkn-1, a process for preparing a recombinant shLkn-1 by employing expression vector therefor and pharmaceutical application of the said protein. shLkn-1 is generated by missing 26 amino acid residues from the amino terminus of Lkn-1 to contain 66 amino acids. Recombinant shLkn-1 inhibits colony formation and cell proliferation in vivo, which suggests that it can be used as a potential drug for the antibody production, the treatment during HIV-1 infection, the protection of bone marrow stem cells during chemotherapy or radiotherapy, and the inhibition of leukemia.

Variant of C6 &bgr;-chemokine leukotactin-1(shLkn-1) with enhanced biological activity

Growing community of inventors

Sungnam-shi, South Korea

Soo-Il Chung