Galvani Bioelectronics Limited

Academisch Medisch Centrum

Presidio Medical, Inc.

Faculdade De Ciências Médicas Da Universidade Nova De Lisboa

Sonal Patel

Daniel John Chew

Hans Jakob Kristoffer Famm

Silvia Margarida Vilares Santos Conde

Brad Holinski

Maria Pedro Sucena Guarino

Wouter Jacob De Jonge

Olaf Welting

The invention refers to a device for inhibiting the neural activity of a carotid sinus nerve (CSN) or carotid body of a subject, the device comprising: one or more transducers configured to apply a signal to the CSN or associated carotid body of the subject, optionally at least two such transducers; and a controller coupled to the one or more transducers, the controller controlling the signal to be applied by the one or more transducers, such that the signal inhibits the neural activity of the CSN or carotid body to produce a physiological response in the subject, wherein the physiological response is one or more of the group consisting of: an increase in insulin sensitivity in the subject, an increase in glucose tolerance in the subject, a decrease in (fasting) plasma glucose concentration in the subject, a reduction in subcutaneous fat content in the subject, and a reduction in obesity in the subject.

Neuromodulation device and method for treating metabolic disorders

The invention provides devices, apparatuses, systems and methods for treating and ameliorating inflammation of the gut. In particular, the invention provides devices, apparatuses and methods in which a neuromodulatory signal is delivered a splenic nerve and/or superior mesenteric plexus (SMP). The signal is able to treat inflammatory disorders, e.g., colitis, for example in Inflammatory Bowel Disease.

Neuromodulation device

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Basel, Switzerland

Sonal Patel